Area of research
Surgery · Cell Biology
Research interest
Research interests include Pancreatic function and diabetes, Hippo pathway signaling and YAP/TAZ, Metabolism, Diabetes, and Cancer, and Diabetes and associated disorders.
The Hippo terminal effector YAP boosts enterovirus replication in type 1 diabetes.
A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis.
MST1 deletion protects β-cells in a mouse model of diabetes.
PHLPP1 deletion restores pancreatic β-cell survival and normoglycemia in the db/db mouse model of obesity-associated diabetes.
The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis.
SARS-CoV-2 and pancreas: a potential pathological interaction?
LDHA is enriched in human islet alpha cells and upregulated in type 2 diabetes.
Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagy.
Hippo STK kinases drive metabolic derangement.