Area of research
Endocrinology, Diabetes and Metabolism · Nutrition and Dietetics
Research interest
Research interests include Clinical Nutrition and Gastroenterology, Hyperglycemia and glycemic control in critically ill and hospitalized patients, Adrenal Hormones and Disorders, and Sepsis Diagnosis and Treatment.
Impact of infusing the cholesterol precursor mevalonate on the hypocholesterolemia of sepsis and its potential consequences: a paradoxical response.
The impact of lipid-rich nutrition on ketogenesis and muscle weakness in sepsis.
Abnormal carnitine concentrations in critical illness associated with compromised outcome.
Abnormalities of liver function during critical illness.
A new era for ICU-acquired weakness research-from mechanisms to meaningful recovery.
Low-Dose Hydrocortisone in Cirrhotic Patients With Septic Shock: A Double-Blind Randomised Placebo-Controlled Trial.
Early phosphate changes as potential indicator of unreadiness for artificial feeding: a secondary analysis of the EPaNIC RCT.
Ketogenic Nutrition in Combination With PPARα Activation Induced Metabolic Failure and Exacerbated Muscle Weakness in Septic Mice.
A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart.
A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging.
A single-center exploratory trial evaluating the pharmacokinetic profile and the metabolic effects of a ketone ester food supplement in intensive care patients: The KETOCARE 2 trial
Alterations in the lipid profile of critically ill children in relation to outcome.
Impact of rAAV-shRNA treatment targeting mechanosensitive Ilk1 and Fermt2 in a mouse model of sepsis-induced muscle weakness.
Our Scientific Journey through the Ups and Downs of Blood Glucose Control in the ICU.
Glucocorticoid treatment increases cholesterol availability during critical illness: effect on adrenal and muscle function.
Pro-opiomelanocortin and ACTH-cortisol dissociation during pediatric cardiac surgery.
The Hypothalamus-pituitary-adrenocortical Response to Critical Illness: A Concept in Need of Revision.
Impact of critical illness on cholesterol and fatty acids: insights into pathophysiology and therapeutic targets.
Development of muscle weakness in a mouse model of critical illness: does fibroblast growth factor 21 play a role?
The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies.
A single-centre, cross-over trial evaluating the metabolic effects of a ketone ester food supplement in intensive care patients
The hypothalamus-pituitary-adrenal axis in sepsis- and hyperinflammation-induced critical illness: Gaps in current knowledge and future translational research directions.
Obesity attenuates inflammation, protein catabolism, dyslipidaemia, and muscle weakness during sepsis, independent of leptin.
Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness.
Impact of duration of critical illness and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: A prospective, observational, cross-sectional human and two translational mouse studies.
Impact of Hydrocortisone and of CRH Infusion on the Hypothalamus-Pituitary-Adrenocortical Axis of Septic Male Mice.
Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research.
C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery.
Correction: Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research.
Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation.