Area of research
Epidemiology · Molecular Medicine
Research interest
Research interests include Burkholderia infections and melioidosis, Antibiotic Resistance in Bacteria, Vibrio bacteria research studies, and Bacterial Genetics and Biotechnology.
Essentiality of the virulence plasmid-encoded factors in disease pathogenesis of the major lineage of hypervirulent Klebsiella pneumoniae varies in different infection niches
Carbene formation as a mechanism for efficient intracellular uptake of cationic antimicrobial carbon acid polymers
Anti-plasmid defense in hypervirulent <i>Klebsiella pneumoniae</i> involves Type I-like and Type IV restriction modification systems
Short-chain fatty acids of various lengths differentially inhibit <i>Klebsiella pneumoniae</i> and <i>Enterobacteriaceae</i> species
Hypervirulent <i>Klebsiella pneumoniae</i> employs genomic island encoded toxins against bacterial competitors in the gut
Carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae with a highly transmissible dual-carbapenemase plasmid in Chile
RIL-seq reveals extensive involvement of small RNAs in virulence and capsule regulation in hypervirulent <i>Klebsiella pneumoniae</i>
Burkholderia thailandensis uses a type VI secretion system to lyse protrusions without triggering host cell responses
Inorganic Polyphosphate Affects Biofilm Assembly, Capsule Formation, and Virulence of Hypervirulent ST23 <i>Klebsiella pneumoniae</i>
A cationic main-chain poly(carbonate-imidazolium) potent against Mycobacterium abscessus and other resistant bacteria in mice
Acquisition of regulator on virulence plasmid of hypervirulent <i>Klebsiella</i> allows bacterial lifestyle switch in response to iron
A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria
Copper-Nanoparticle-Coated Fabrics for Rapid and Sustained Antibacterial Activity Applications
Long-term ecological and evolutionary dynamics in the gut microbiomes of carbapenemase-producing Enterobacteriaceae colonized subjects
New roles for glutathione: Modulators of bacterial virulence and pathogenesis
Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut
A Glycosylated Cationic Block Poly(β‐peptide) Reverses Intrinsic Antibiotic Resistance in All ESKAPE Gram‐Negative Bacteria
cGAS-STING pathway in oncogenesis and cancer therapeutics
Cell envelope defects of different capsule‐null mutants in K1 hypervirulent<i>Klebsiella pneumoniae</i>can affect bacterial pathogenesis
Acquisition of Plasmid with Carbapenem-Resistance Gene <i>bla</i><sub>KPC2</sub> in Hypervirulent <i>Klebsiella pneumoniae</i>, Singapore
Bacterium‐Templated Polymer for Self‐Selective Ablation of Multidrug‐Resistant Bacteria
Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
Designer broad-spectrum polyimidazolium antibiotics
Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination
Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population
Host Cytosolic Glutathione Sensing by a Membrane Histidine Kinase Activates the Type VI Secretion System in an Intracellular Bacterium
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei
Host Susceptibility Factors to Bacterial Infections in Type 2 Diabetes
<i>Burkholderia pseudomallei</i> suppresses <i>Caenorhabditis elegans</i> immunity by specific degradation of a GATA transcription factor
Glutathione deficiency in type 2 diabetes impairs cytokine responses and control of intracellular bacteria