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Lillian L. Siu

University Health Network · CA
Area of research
Oncology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Head and Neck Cancer Studies, and Lung Cancer Treatments and Mutations.
h-index
101
citations
41,143
works
1,279
NIH funding
primary concept
email

Recent publications

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial
Nature Medicine 2025cited by 89position: middledoi
INTERLINK-1: A Phase III, Randomized, Placebo-Controlled Study of Monalizumab plus Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Clinical Cancer Research 2025cited by 16position: middledoi
LiGeR-HN phase III trials of petosemtamab + pembrolizumab and petosemtamab monotherapy in recurrent or metastatic HNSCC
Future Oncology 2025cited by 6position: middledoi
Precision cancer medicine: Concepts, current practice, and future developments
Journal of Internal Medicine 2023cited by 69position: middledoi
Targeting the Inducible T-cell Costimulator (ICOS) in Patients with Relapsed/Refractory T-follicular Helper Phenotype Peripheral T-cell and Angioimmunoblastic T-cell Lymphoma
Clinical Cancer Research 2023cited by 32position: lastdoi
854O INTERLINK-1: Phase III study of cetuximab (CTX) ± monalizumab (M) in participants (pts) with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) with disease progression on/after platinum chemotherapy (CT) and previously treated with an immune checkpoint inhibitor (ICI)
Annals of Oncology 2023cited by 32position: middledoi
A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies
OncoImmunology 2023cited by 25position: middledoi
Data from A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kβ/δ, in Patients with Advanced Solid Tumors
2023cited by 0position: middledoi
First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors
Clinical Cancer Research 2022cited by 80position: lastdoi
A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kβ/δ, in Patients with Advanced Solid Tumors
Clinical Cancer Research 2022cited by 40position: middledoi
Phase Ib study of anetumab ravtansive in combination with immunotherapy or immunotherapy plus chemotherapy in mesothelin-enriched advanced pancreatic adenocarcinoma: NCI10208.
Journal of Clinical Oncology 2022cited by 12position: middledoi
Molecular profiling for precision cancer therapies
Genome Medicine 2020cited by 891position: lastdoi
Small molecules, big impact: 20 years of targeted therapy in oncology
The Lancet 2020cited by 597position: lastdoi
Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study
Clinical Cancer Research 2020cited by 107position: lastdoi
How liquid biopsies can change clinical practice in oncology
Annals of Oncology 2019cited by 350position: middledoi
Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion
Journal of Clinical Oncology 2019cited by 72position: middledoi
Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy
JNCI Journal of the National Cancer Institute 2019cited by 72position: middledoi
BMS-986205, an indoleamine 2, 3-dioxygenase 1 inhibitor (IDO1i), in combination with nivolumab (nivo): Updated safety across all tumor cohorts and efficacy in advanced bladder cancer (advBC).
Journal of Clinical Oncology 2019cited by 57position: middledoi
Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours
European Journal of Cancer 2019cited by 29position: middledoi
Abstract B057: BMS-986148, an anti-mesothelin antibody-drug conjugate (ADC), alone or in combination with nivolumab demonstrates clinical activity in patients with select advanced solid tumors
Molecular Cancer Therapeutics 2019cited by 18position: middledoi
Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1–Low/Negative Recurrent or Metastatic HNSCC
JAMA Oncology 2018cited by 309position: firstdoi
Durvalumab for recurrent or metastatic head and neck squamous cell carcinoma: Results from a single-arm, phase II study in patients with ≥25% tumour cell PD-L1 expression who have progressed on platinum-based chemotherapy
European Journal of Cancer 2018cited by 265position: middledoi
A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer
Targeted Oncology 2017cited by 95position: middledoi
Abstract CT116: BMS-986205, an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic (PD) activity, alone and in combination with nivolumab (nivo) in advanced cancers in a phase 1/2a trial
Cancer Research 2017cited by 86position: firstdoi
A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma
Oncotarget 2017cited by 68position: middledoi
Toward understanding and exploiting tumor heterogeneity
Nature Medicine 2015cited by 766position: middledoi
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs
Mayo Clinic Proceedings 2015cited by 144position: middledoi
Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies
Investigational New Drugs 2015cited by 42position: middledoi
Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors
Clinical Cancer Research 2015cited by 25position: middledoi
Tumour heterogeneity in the clinic
Nature 2013cited by 1,210position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Jérôme Fayette · Université Claude Bernard Lyon 14 papers (2018–2025)Aaron R. Hansen · Princess Alexandra Hospital3 papers (2013–2017)Kevin J. Harrington · NIHR Biomedical Research Centre at The Royal Marsden and the ICR3 papers (2020–2025)Irene Braña · Universitat de Vic - Universitat Central de Catalunya3 papers (2017–2018)Giuseppe Curigliano · Istituti di Ricovero e Cura a Carattere Scientifico2 papers (2019–2019)Makoto Tahara · National Cancer Center Hospital East2 papers (2023–2025)Quynh‐Thu Le · Stanford University2 papers (2019–2019)Josep Tabernero · Medical Research Network2 papers (2017–2019)Paul Basciano · NKT Therapeutics (United States)2 papers (2017–2019) · 2 papers (2018–2018)Dan P. Zandberg · University of Pittsburgh2 papers (2018–2018)Ricard Mesı́a · Universitat Autònoma de Barcelona2 papers (2018–2018)Philippe L. Bédard · University Health Network2 papers (2013–2020)Danny Rischin · Peter MacCallum Cancer Centre2 papers (2020–2023)Amanda Psyrri · Hellenic Cooperative Oncology Group2 papers (2023–2025)Christophe Le Tourneau · Inserm2 papers (2023–2025)Ulrich Keilholz · German Marine Research Consortium2 papers (2018–2023)Karen A. Gelmon · BC Cancer Agency2 papers (2017–2019)Sandip Pravin Patel · Hindu College of Pharmacy2 papers (2019–2019)Ulrik Lassen · Institut Bergonié2 papers (2015–2023)