Area of research
Cancer Research · Plant Science
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Plant Physiology and Cultivation Studies, Immune cells in cancer, and Adipose Tissue and Metabolism.
A century of the Warburg effect
Glutarate regulates T cell metabolism and anti-tumour immunity
Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells
Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy
Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses
Infiltration of Tumors Is Regulated by T cell–Intrinsic Nitric Oxide Synthesis
Oxygen regulation of TET enzymes
Modified Hypoxia-Inducible Factor Expression in CD8+ T Cells Increases Antitumor Efficacy
Cytotoxic T-cells mediate exercise-induced reductions in tumor growth
The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome
Deregulated hypoxic response in myeloid cells: A model for high‐altitude pulmonary oedema (HAPE)
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia
The role of Olfr78 in the breathing circuit of mice
HIF-2α is essential for carotid body development and function
Rootstock performance in the 2009 NC-140 peach trial across 11 states
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase
S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate
Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection
HIF2α–arginase axis is essential for the development of pulmonary hypertension
HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes
Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells
HIF Transcription Factors, Inflammation, and Immunity
Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis
Tumour oxygenation: implications for breast cancer prognosis
HIF isoforms in the skin differentially regulate systemic arterial pressure
Activation of Hypoxia‐Inducible Factor‐2 in Adipocytes Results in Pathological Cardiac Hypertrophy