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Karl Tryggvason

Singapore Eye Research Institute · SG
Area of research
Nephrology · Immunology and Allergy
Research interest
Research interests include Cell Adhesion Molecules Research, Renal Diseases and Glomerulopathies, Protease and Inhibitor Mechanisms, and Chronic Kidney Disease and Diabetes.
h-index
114
citations
47,278
works
487
NIH funding
primary concept
email

Recent publications

Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs
npj Regenerative Medicine 2023cited by 20position: lastdoi
Skin mesenchymal niches maintain and protect AML-initiating stem cells.
2023cited by 5position: contributordoi
A high-resolution map of human RNA translation
Molecular Cell 2022cited by 149position: middledoi
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system.
2022cited by 34position: contributordoi
Evaluating Capture Sequence Performance for Single-Cell CRISPR Activation Experiments.
2021cited by 5position: contributordoi
Laminins in Cellular Differentiation
Trends in Cell Biology 2019cited by 135position: lastdoi
In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors
Cell Reports 2019cited by 59position: lastdoi
Culturing functional pancreatic islets on α5-laminins and curative transplantation to diabetic mice
Matrix Biology 2018cited by 46position: lastdoi
Ab initio solution of macromolecular crystal structures without direct methods
Proceedings of the National Academy of Sciences 2017cited by 66position: middledoi
Human embryonic stem cells
Best Practice & Research Clinical Obstetrics & Gynaecology 2015cited by 63position: middledoi
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment
Nature Communications 2014cited by 289position: lastdoi
Monolayer culturing and cloning of human pluripotent stem cells on laminin-521–based matrices under xeno-free and chemically defined conditions
Nature Protocols 2014cited by 102position: lastdoi
Laminin α4 Deficient Mice Exhibit Decreased Capacity for Adipose Tissue Expansion and Weight Gain
PLoS ONE 2014cited by 64position: lastdoi
Chromosome 2q31.1 Associates with ESRD in Women with Type 1 Diabetes
Journal of the American Society of Nephrology 2013cited by 74position: middledoi
Functional Diversity of Laminins
Annual Review of Cell and Developmental Biology 2012cited by 396position: lastdoi
New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes
PLoS Genetics 2012cited by 281position: middledoi
Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria
Cell Metabolism 2012cited by 203position: middledoi
MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis
Developmental Cell 2012cited by 84position: middledoi
Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation
Kidney International 2012cited by 64position: middledoi
Towards understanding the inherited susceptibility for nephropathy in diabetes
Current Opinion in Nephrology & Hypertension 2012cited by 57position: lastdoi
New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes
Research Portal (Queen's University Belfast) 2012cited by 0position: middle

Grants

No grants ingested yet.

Frequent collaborators

Sergey Rodin · Uppsala University5 papers (2012–2018)Outi Hovatta · Karolinska Institutet4 papers (2014–2019)Li Yen Chong · National University of Singapore4 papers (2014–2023)Anna Domogatskaya · Karolinska Institutet3 papers (2012–2018)Enrico Petretto · China Pharmaceutical University3 papers (2018–2023)Liselotte Antonsson · Karolinska University Hospital3 papers (2014–2015)Lynn Yap · National University of Singapore3 papers (2019–2023) · 3 papers (2021–2023)Miina K. Öhman · National University of Singapore2 papers (2018–2019)Aida Moreno‐Moral · National University of Singapore2 papers (2018–2019)Per‐Henrik Groop · University of Helsinki2 papers (2012–2013)Zhongjun Zhou · University of Electronic Science and Technology of China2 papers (2012–2012)Guoxiang Jin · Wake Forest University2 papers (2012–2012)Christer Betsholtz · Uppsala University2 papers (2012–2014)Pauliina Damdimopoulou · Karolinska University Hospital2 papers (2014–2015)Stuart A. Cook · University of Otago2 papers (2019–2022)Baohua Liu · Shenzhen University Health Science Center2 papers (2012–2012)Juha Ojala · Karolinska Institutet2 papers (2017–2018)Lynn Yap · 2 papers (2021–2022)Nathan Harmston · Cardiff University2 papers (2019–2022)