Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Pancreatic and Hepatic Oncology Research, Trypanosoma species research and implications, and Epigenetics and DNA Methylation.
PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
Gut microbiota deficiency reduces neutrophil activation and is protective after ischemic stroke
Sorafenib as first-line therapy for metastatic uveal melanoma: A multicenter, placebo-controlled randomized discontinuation study (STREAM)
Redirecting resistance evolution in <i> BRAF <sup>V600</sup> </i> melanoma by inhibition of the peroxiredoxin-thioredoxin system
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion
Minimally invasive determination of pancreatic ductal adenocarcinoma ( <scp>PDAC</scp> ) subtype by means of circulating cell‐free <scp>RNA</scp>
Minimally invasive determination of PDAC subtype and therapy-induced subtype switch by means of circulating cell-free RNA
SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis
Coinhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription
Progranulin mediates immune evasion of pancreatic ductal adenocarcinoma through regulation of MHCI expression
Persister state-directed transitioning and vulnerability in melanoma
Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype
The clinical utility of <scp>cfRNA</scp> for disease detection and surveillance: A proof of concept study in non‐small cell lung cancer
Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma
The DKTK EXLIQUID consortium – exploiting liquid biopsies to advance cancer precision medicine for molecular tumor board patients
Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients
<i>SOX2</i> dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the <i>FOSL2/IL6</i> axis
Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer
Functional metabolic phenotyping of human pancreatic ductal adenocarcinoma
TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer
Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer
The predictive and prognostic significance of cell‐free DNA concentration in melanoma
Serial Circulating Tumor DNA Mutational Status in Patients with <i>KRAS</i>-Mutant Metastatic Colorectal Cancer from the Phase 3 AIO KRK0207 Trial
The TP63 Gene Polymorphism rs17506395 is Associated with Early Breast Cancer in Cameroon
Persister state-directed transitioning and vulnerability in melanoma
Association between Polymorphisms of SNPs Located at the 3’-Untranslated Region of SET8 and Codon 72 of the TP53 with Breast Cancer among Cameroonian Women
The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation
Immunoprofiling of Chlamydia trachomatis using whole-proteome microarrays generated by on-chip in situ expression
Personalised proteome analysis by means of protein microarrays made from individual patient samples
Gene expression regulatory networks in <scp><i>T</i></scp><i>rypanosoma brucei</i>: insights into the role of the mRNA‐binding proteome