Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research interests include Malaria Research and Control, Mosquito-borne diseases and control, vaccines and immunoinformatics approaches, and Invertebrate Immune Response Mechanisms.
Malaria vaccine protection against intradermal or venous parasites: a randomized phase 2b human challenge trial.
Safety and Efficacy of Two Attenuated PfSPZ Vaccines in Malaria Inexperienced Soldiers Exposed to Plasmodium Falciparum Malaria Genetically Distant from the Vaccine Strain during Deployment to Papua Province, Indonesia
Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine
Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults
Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms.
A paradigm for Africa-centric vaccine development in Equatorial Guinea
Sporozoite immunization: innovative translational science to support the fight against malaria.
Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies
A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection.
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria.
Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria
In vitro production of infectious Plasmodium falciparum sporozoites.
Clonal evolution and TCR specificity of the human T <sub>FH</sub> cell response to <i>Plasmodium falciparum</i> CSP
Clonal evolution and TCR specificity of the human T<sub>FH</sub> cell response to <i>Plasmodium falciparum</i> CSP.
Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa.
Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens.
The exception that proves the rule: Virulence gene expression at the onset of
<i>Plasmodium falciparum</i>
blood stage infections
Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity
Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial.
Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence.
An efficient single‐cell based method for linking human T cell phenotype to T cell receptor sequence and specificity
Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome.
Clonal evolution and specificity of the human T follicular helper cell response to <i>Plasmodium falciparum</i> circumsporozoite protein
Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence
A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1.
Activation of TCR Vδ1<sup>+</sup> and Vδ1<sup>-</sup>Vδ2<sup>-</sup> γδ T Cells upon Controlled Infection with <i>Plasmodium falciparum</i> in Tanzanian Volunteers.
Serologic Markers of Previous Malaria Exposure and Functional Antibodies Inhibiting Parasite Growth Are Associated With Parasite Kinetics Following a Plasmodium falciparum Controlled Human Infection
Malaria vaccine trials in pregnant women: An imperative without precedent
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Clonal selection drives protective memory B cell responses in controlled human malaria infection