Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Congenital heart defects research, Carbon Nanotubes in Composites, Congenital Heart Disease Studies, and Pluripotent Stem Cells Research.
The oligogenic inheritance test GCOD detects risk genes and their interactions in congenital heart defects.
Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21.
Genome-wide CRISPRi screen identifies basigin loss as protective in cardiac hypoxia
Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes
The maternal X chromosome affects cognition and brain ageing in female mice
The maternal X chromosome affects cognition and brain ageing in female mice.
Recessive genetic contribution to congenital heart disease in 5,424 probands
Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21.
A microphysiological system for screening lipid nanoparticle-mRNA complexes predicts in vivo heart transfection efficacy.
MitoScribe single-cell molecular recorder logs graded signaling dynamics into mitochondrial DNA
Uncovering Developmental Origins of Aortic Valve Disease
Chromatin remodelling drives immune cell–fibroblast communication in heart failure
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Human spinal interneurons repair the injured spinal cord through synaptic integration
Improved Cardiac Function in Postischemic Rats Using an Optimized Cardiac Reprogramming Cocktail Delivered in a Single Novel Adeno-Associated Virus.
Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease
A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors.
Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease.
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes
The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5.
Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes.
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes.
Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies.
Transcription factor protein interactomes reveal genetic determinants in heart disease
Transcription factor protein interactomes reveal genetic determinants in heart disease.
Transient Cell Cycle Induction in Cardiomyocytes to Treat Subacute Ischemic Heart Failure.
Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.
Cold shock domain–containing protein E1 is a posttranscriptional regulator of the LDL receptor
Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.