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Nikki K. Lytle

Medical College of Wisconsin · US
Area of research
Oncology · Biotechnology
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Cancer Cells and Metastasis, Cancer Research and Treatments, and Pancreatitis Pathology and Treatment.
h-index
21
citations
2,999
works
56
NIH funding
primary concept
Medicine
email

Recent publications

(Lytle NK, Wood LD.) Dev Cell. 2026 May 13;61(5):971-972 PMID: 42127806 05/14/2026
2026cited by 0position: selected
(Thalji SZ, Aldakkak M, Ramamurthi A, Jaraczewski TJ, Belbahri M, SenthilKumar G, Shaik T, Merrill JR, Banerjee A, Taylor BW, Kamgar M, George B, Erickson B, Hall WA, Lytle NK, Seo YD, Christians KK, Clarke CN, Evans DB, Tsai S, Kothari AN.) JAMA Surg. 2026 May 01;161(5):508-516 PMID: 41848749 PMCID
2026cited by 0position: selected
(Kamgar M, Hobbes GA, Davidson R, Dorbin D, Herrera J, Langenheim JF, Burge RA, Aldakkak M, Conrardy RD, Szabo A, Thalji SZ, Mayer B, Grahl JJ, Chung BY, Phan A, Thomas JP, Seo YD, Evans DB, Christians KK, Erickson B, Hall WA, George B, Tsai S, Lytle NK, Der CJ, Kurzrock R, McFall T.) Cancer Res. 20
2026cited by 0position: selected
(Vallmajo-Martin Q, Ma Z, Srinivasan S, Murali D, Dravis C, Mukund K, Subramaniam S, Wahl GM, Lytle NK.) bioRxiv. 2024 Nov 04 PMID: 39415993 PMCID: PMC11482796 10/17/2024
2024cited by 0position: selected
(Rajbhandari N, Hamilton M, Quintero CM, Ferguson LP, Fox R, Schürch CM, Wang J, Nakamura M, Lytle NK, McDermott M, Diaz E, Pettit H, Kritzik M, Han H, Cridebring D, Wen KW, Tsai S, Goggins MG, Lowy AM, Wechsler-Reya RJ, Von Hoff DD, Newman AM, Reya T.) Cancer Cell. 2023 Nov 13;41(11):1989-2005.e9 P
2023cited by 0position: selected
(Ferguson LP, Gatchalian J, McDermott ML, Nakamura M, Chambers K, Rajbhandari N, Lytle NK, Rosenthal SB, Hamilton M, Albini S, Wartenberg M, Zlobec I, Galván JA, Karamitopoulou E, Vavinskaya V, Wascher A, Lowy AM, Schürch CM, Puri PL, Bruneau BG, Hargreaves DC, Reya T.) Nat Commun. 2023 Jan 18;14(1)
2023cited by 0position: selected
(Ma Z, Lytle NK, Chen B, Jyotsana N, Novak SW, Cho CJ, Caplan L, Ben-Levy O, Neininger AC, Burnette DT, Trinh VQ, Tan MCB, Patterson EA, Arrojo E Drigo R, Giraddi RR, Ramos C, Means AL, Matsumoto I, Manor U, Mills JC, Goldenring JR, Lau KS, Wahl GM, DelGiorno KE.) Gastroenterology. 2022 Feb;162(2):6
2022cited by 0position: selected
(Gubbala VB, Jytosana N, Trinh VQ, Maurer HC, Naeem RF, Lytle NK, Ma Z, Zhao S, Lin W, Han H, Shi Y, Hunter T, Singh PK, Olive KP, Tan MCB, Kaech SM, Wahl GM, DelGiorno KE.) Gastro Hep Adv. 2022;1(4):682-697 PMID: 36277993 PMCID: PMC9583893 10/25/2022
2022cited by 0position: selected
(Ma Z, Lytle NK, Ramos C, Naeem RF, Wahl GM.) Methods Mol Biol. 2022;2471:49-82 PMID: 35175591 PMCID: PMC9663269 02/18/2022
2022cited by 0position: selected
Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury
Gastroenterology 2021cited by 110position: middledoi
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
Nature 2021cited by 3position: middledoi
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2
Gastroenterology 2020cited by 88position: middledoi
(Spinler K, Bajaj J, Ito T, Zimdahl B, Hamilton M, Ahmadi A, Koechlein CS, Lytle N, Kwon HY, Anower-E-Khuda F, Sun H, Blevins A, Weeks J, Kritzik M, Karlseder J, Ginsberg MH, Park PW, Esko JD, Reya T.) Nat Commun. 2020 Nov 26;11(1):5998 PMID: 33243988 PMCID: PMC7691523 11/28/2020
2020cited by 0position: selected
(DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wa
2020cited by 0position: selected
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
Nature 2019cited by 424position: middledoi
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma
Cell 2019cited by 170position: firstdoi
Stem cell fate in cancer growth, progression and therapy resistance
Nature reviews. Cancer 2018cited by 667position: firstdoi
Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity
Cancer Cell 2018cited by 141position: middledoi
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
Cancer Cell 2017cited by 127position: middledoi
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
Nature 2016cited by 146position: middledoi
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia
Cancer Cell 2016cited by 122position: middledoi
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia
Cell stem cell 2015cited by 78position: middledoi
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade
Proceedings of the National Academy of Sciences 2014cited by 108position: middledoi
The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila
PLoS ONE 2013cited by 56position: middledoi
Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia
Journal of Clinical Investigation 2012cited by 93position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Tannishtha Reya · Columbia University Irving Medical Center7 papers (2014–2018)Jeevisha Bajaj · University of Rochester Medical Center3 papers (2015–2016)Vivian G. Oehler · Yale Cancer Center2 papers (2015–2016)Hyog Young Kwon · Soonchunhyang University2 papers (2015–2016)Takahiro Ito · Kyoto University2 papers (2015–2016)Claire S. Koechlein · University of California San Diego2 papers (2015–2016)Geoffrey M. Wahl · Salk Institute for Biological Studies2 papers (2018–2021)Roman Šášik · University of California San Diego2 papers (2015–2016)Michael Karin · Discovery Institute2 papers (2014–2017)Mark A. Valasek · Bryan College2 papers (2016–2017)David A. Rizzieri · Novant Health2 papers (2015–2016)Charles Chuah · SingHealth2 papers (2015–2016)Takaaki Konuma · The University of Tokyo2 papers (2015–2016)Xuefeng Wu · East China Jiaotong University2 papers (2014–2017)Raymond G. Fox · Frederick National Laboratory for Cancer Research2 papers (2014–2016)Christy L. Trejo · Drip Research Technology Services (United States)1 papers (2018–2018)Jason K. Sicklick · University of San Diego1 papers (2016–2016) · 1 papers (2014–2014)Joan Font-Burgada · Fox Chase Cancer Center1 papers (2014–2014)Hai‐Ying Shen · Sichuan Provincial Hospital of Traditional Chinese Medicine1 papers (2012–2012)