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Dung‐Tsa Chen

Moffitt Cancer Center · US
Area of research
Oncology · Immunology
Research interest
Dr. Chen has been on numerous NCI grants as a co-investigator involving in the design, conduct, and analysis of research projects in cancer and has over 100 peer-reviewed publications. His key areas of expertise include microarray data analysis, mixed models, survival data analysis, biomarker analysis and clinical trials.His work involves the identification of novel biomarker strategies using genomics and other emerging technologies to guide clinical decision making. He has developed a statistical outlier approach to derive a malignancy-risk gene signature in breast cancer. This statistical outlier method has potential unique applications in cancer research, such as improved prediction of cancer risk, thereby providing better individualized therapy. Statistical outlier methods could be useful tools to help identify subgroups of individuals who may have high risk of cancer development and need special chemopreventive treatments. For example, an outlier gene signature to identifying high-risk normal breast tissue could improve the potential for breast biopsy to identify at-risk patients and refine the current practice of intraoperative assessment of the margins of the resected breast tissues based on histology alone, and may prove useful in guiding treatment choices after lumpectomy.
h-index
36
citations
4,935
works
320
NIH funding
primary concept
Medicine
email

Recent publications

HER-2 Altered Early-Stage Non-Small Cell Lung Cancer Had Better Survival than Triple-Negative Disease.
2026cited by 0position: contributordoi
Tanvetyanon T, Chen DT, Gray JE. HER-2 Altered Early-Stage Non-Small Cell Lung Cancer Had Better Survival than Triple-Negative Disease. J Clin Med. 2026 May.15(9). Pubmedid: 42123214 . Pmcid: PMC13164032.
2026cited by 0position: selected
Tanvetyanon T, Joshi U, Chen DT, Gray JE. Timeliness of Newer Targeted Therapy and Survival in Lung Cancer: A Population-Based Analysis. JCO Oncol Pract. 2026 Mar.22(3):410-417. Pubmedid: 40472300 .
2026cited by 0position: selected
Obermayer A, Davis J, Talada DP, Teng M, Eschrich S, Yin V, Spakowicz D, Chatterjee D, Rounbehler RJ, Churchman ML, Tarhini AA, Wang X, Gupta S, Markowitz J, Goecks J, Li R, Rodrigues Pessoa R, Manley BJ, Tan AC, Grass GD, Chen DT, Shaw TI. ShinyEvents: harmonizing longitudinal data for real-world s
2026cited by 0position: selected
Lantz AE, Gebert R, Li J, Oliveras JA, Gordián ER, Perez-Morales J, Eschrich S, Chen DT, Rosa M, Dutil J, Saavedra HI, Muñoz-Antonia T, Flores I, Cress WD. Worse Clinical and Survival Outcomes in Breast Cancer Patients Living in Puerto Rico Compared to Hispanics, Non-Hispanic Blacks, and Non-Hispani
2026cited by 0position: selected
Ozakinci H, Desai B, Kalos D, Chen DT, Henry M, Solanki H, Boyle TA, Trejo Bittar HE, Nazario GS, Haura EB, Marusyk A, Pellini B. Pre-clinical efficacy of trastuzumab deruxtecan plus sotorasib in KRAS -mutant non-small cell lung cancer and exploratory HER2 profiling in human tumors. Transl Lung Canc
2026cited by 0position: selected
Tanvetyanon T, Chen DT, Gray JE. Relationship between PD-L1 Expression and Outcomes of Salvage Treatment Following Durvalumab Consolidation. Clin Lung Cancer. 2026 Apr.27(3):135-143. Pubmedid: 41238478 .
2026cited by 0position: selected
Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy.
2025cited by 4position: contributordoi
The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Cancer Epidemiology Biomarkers & Prevention 2025cited by 3position: middledoi
Phase 1 trial of hypofractionated stereotactic re-irradiation in combination with nivolumab, ipilimumab, and bevacizumab for recurrent high-grade gliomas.
2025cited by 2position: contributordoi
A sample size analysis of a mathematical model of longitudinal tumor volume and progression-free survival for Bayesian individual dynamic predictions in recurrent high-grade glioma.
2025cited by 1position: contributordoi
Integrative Immune Signature of Complementary Circulating and Tumoral Biomarkers Maximizes the Predictive Power of Adjuvant Immunotherapeutic Benefits in High-risk Melanoma.
2025cited by 1position: contributordoi
Creation and Characterization of a Breast Cancer Tissue Microarray Including Black and White Patients from Florida and Hispanic Patients from Puerto Rico and Florida.
2025cited by 1position: contributordoi
Timing of Durvalumab Consolidation and Survival in Non-Small Cell Lung Cancer: A Population-Based Analysis.
2025cited by 0position: contributordoi
Race-based differences in serum biomarkers for cancer-associated cachexia in a diverse cohort of patients with pancreatic ductal adenocarcinoma.
2025cited by 0position: contributordoi
The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma.
2025cited by 0position: contributordoi
DeSomma A, Maletz S, Basinski TL, Morales R, de Castria TB, Bloomston M, Chen DT, Douglas WG, Huguet KL, Jeong D, Jiang K, Kim DW, Luthra A, Pimiento JM, Rajasekhara S, Velanovich V, Park MA, Shields GS, Slavich GM, Permuth JB. Lifetime stressor exposure and depression among patients with pancreatic
2025cited by 0position: selected
Lantz AE, Gordián ER, Rosa M, Rodríguez Ruíz M, Johnson JO, Gebert R, Bahr A, Chen DT, Dutil J, Li J, Oliveras Torres JA, Saavedra HI, Eschrich SA, Flores I, Cress WD. Creation and Characterization of a Breast Cancer Tissue Microarray Including Black and White Patients from Florida and Hispanic Pati
2025cited by 0position: selected
Glazar DJ, Sahebjam S, Yu HM, Chen DT, Bhandari M, Enderling H. A sample size analysis of a mathematical model of longitudinal tumor volume and progression-free survival for Bayesian individual dynamic predictions in recurrent high-grade glioma. CPT Pharmacometrics Syst Pharmacol. 2025 Mar.14(3):495
2025cited by 0position: selected
Marin-Acevedo JA, Thapa R, Bandikatla SV, Chen DT, Hicks JK, Gray JE, Puri S. Outcomes with frontline immune checkpoint inhibitors among individuals with BRAF-mutant non-small cell lung cancer. Front Oncol. 2025 Dec.15:1681119. Pubmedid: 41450930 . Pmcid: PMC12727587.
2025cited by 0position: selected
Tanvetyanon T, Chen DT, Gray JE. Timing of Durvalumab Consolidation and Survival in Non-Small Cell Lung Cancer: A Population-Based Analysis. JCO Oncol Pract. 2025 Dec.OP2500259. Pubmedid: 41370737 .
2025cited by 0position: selected
Obermayer A, Davis J, Talada DP, Teng M, Eschrich S, Yin V, Spakowicz D, Dhrubo D, Rounbehler RJ, Churchman ML, Tarhini AA, Wang X, Gupta S, Markowitz J, Goecks J, Li R, Rodriguez-Pessoa R, Manley BJ, Tan AC, Grass GD, Chen DT, Shaw TI. ShinyEvents: harmonizing longitudinal data for real world survi
2025cited by 0position: selected
Tarhini AA, Obermayer A, Lee SJ, LaFramboise WA, Hodi FS, Karunamurthy AD, Eljilany I, Chen DT, Hwu P, El Naqa IM, Streicher H, Sondak VK, Storkus WJ, Butterfield LH, Shaw TI, Kirkwood JM. Integrative Immune Signature of Complementary Circulating and Tumoral Biomarkers Maximizes the Predictive Power
2025cited by 0position: selected
Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of treatment-naïve patients with pancreatic ductal adenocarcinoma
Frontiers in Oncology 2024cited by 12position: middledoi
Molecular Pathway and Immune Profile Analysis of IPMN-Derived Versus PanIN-Derived Pancreatic Ductal Adenocarcinomas.
2024cited by 6position: contributordoi
Pancreatic Cyst Size Measurement on Magnetic Resonance Imaging Compared to Pathology.
2024cited by 2position: contributordoi
Molecular Pathway and Immune Profile Analysis of IPMN-Derived versus PanIN-Derived Pancreatic Ductal Adenocarcinomas
2024cited by 0position: contributordoi
Ozakinci H, Song X, Nazario GS, Lila T, Chen B, Simpson T, Nguyen JV, Moran Segura CM, Thompson ZJ, Thapa R, Rose TA, Haura EB, Pellini B, Yu X, Ruffell BH, Chen DT, Boyle TA, Beg AA. Rapid Autopsy to Define Dendritic Cell Spatial Distribution and T Cell Association in Lung Adenocarcinoma. J Immunol
2024cited by 0position: selected
Tanvetyanon T, Chen DT, Gray JE. Timeliness of EGFR/ALK Inhibitor Treatment and Survival in Lung Cancer: A Population-Based Analysis. Clin Lung Cancer. 2024 Nov.25(7):e304-e311. Pubmedid: 38825406 .
2024cited by 0position: selected
Phase 1 Dose Escalation of Stereotactic Body Radiation Therapy and Concurrent Cisplatin for Reirradiation of Unresectable, Recurrent Squamous Cell Carcinoma of the Head and Neck
International Journal of Radiation Oncology*Biology*Physics 2023cited by 10position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 12 papers (2023–2026)Issam El Naqa · University of Florida Health3 papers (2023–2025)Jennifer B. Permuth · Moffitt Cancer Center3 papers (2016–2021) · 3 papers (2023–2025)Jennifer B. Permuth · Yale University3 papers (2024–2025)Jamie K. Teer · University of South Florida3 papers (2024–2025)Jung Woo Choi · University of Florida2 papers (2016–2019)Zobeida Cruz‐Monserrate · Crowell & Moring (United States)2 papers (2024–2024)Nipun B. Merchant · University of Miami2 papers (2016–2019)Tawee Tanvetyanon · Moffitt Cancer Center2 papers (2025–2026)Jose Trevino · Virginia Commonwealth University2 papers (2016–2019)Solmaz Sahebjam · University of Baltimore2 papers (2025–2025) · 2 papers (2025–2026)John M. Koomen · Florida College2 papers (2025–2025)Paul Stewart · University of South Florida2 papers (2024–2025)Zihai Li · Neurological Surgery1 papers (2025–2025)Michelle Echevarria · Moffitt Cancer Center1 papers (2023–2023)Estrella M. Carballido · University of South Florida1 papers (2019–2019)Daniel Jeong · University of Florida1 papers (2019–2019)Mokenge P. Malafa · University of South Florida1 papers (2016–2016)