Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Chemistry, Stereochemistry, Lycopodium, Cytotoxic T cell, Moiety, and Alkaloid.
Dehydrotrametenolic acid methyl ester, a triterpenoid of Poria cocos, alleviates non-alcoholic steatohepatitis by suppressing NLRP3 inflammasome activation via targeting Caspase-1 in mice
A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization
Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation
Unified Strategy Enables the Collective Syntheses of Structurally Diverse Indole Alkaloids
The Chemistry and Biology of <i>Lycopodium</i> Alkaloids
Lycopodium alkaloids from Huperzia serrata and their cholinesterase inhibitory activities
Phenolic Components and Biological Activity of Pomegranate
In vitro and vivo anti-tumor activity and mechanisms of the new cryptotanshinone derivative 11 against hepatocellular carcinoma
Lycocasine A, a Lycopodium Alkaloid from Lycopodiastrum casuarinoides and Its Acid-Sensing Ion Channel 1a Inhibitory Activity
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition
Discovery and Biomimetic Semisynthesis of Spirophyllines A–D from <i>Uncaria rhynchophylla</i>
Casuattimines A–N, fourteen new Lycopodium alkaloids from Lycopodiastrum casuarinoides with Cav3.1 channel inhibitory activity
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RARα-PPARγ-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase
Hypoestins A–D: highly modified fusicoccane diterpenoids with promising Ca<sub>v</sub>3.1 calcium channel inhibitory activity from <i>Hypoestes purpurea</i>
Eleven undescribed alkaloids from the rhizomes of Sinomenium acutum and their IDO1 and TDO inhibitory activities
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
Design, synthesis and biological evaluation of a new class of Hsp90 inhibitors vibsanin C derivatives
Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of NMDA receptors
Spiroligustolides A and B: Two pairs of enantiomeric spiro-orthoester-containing phthalide dimers as Cav3.1 calcium channel inhibitors from Ligusticum Chuanxiong Hort
Hupertimines A–E, Fawcettimine‐Type <i>Lycopodium</i> Alkaloids from <i>Huperzia serrata</i>
An Approach for the Synthesis of Pyrazolo[1,5-<i>a</i>]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles
Rhynchines A–E: Ca<sub>v</sub>3.1 Calcium Channel Blockers from <i>Uncaria rhynchophylla</i>
Polar auxin transport May Be responsive to specific features of flavonoid structure
Cassane diterpenoids from the seeds of Caesalpinia bonduc and their nitric oxide production and α-glucosidase inhibitory activities
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
Vibsane‐Type Diterpenoids: Structures, Derivatives, Bioactivities, and Synthesis
Tetranorlanostane and Lanostane Triterpenoids with Cytotoxic Activity from the Epidermis of <i>Poria cocos</i>
<i>Neo</i>‐clerodane Diterpenoids with Hypoglycemic Effects <i>in Vivo</i> from the Aerial Parts of <i>Salvia hispanica</i> L.