Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and Immunotherapy and Immune Responses.
HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia
T cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges
A spatial human thymus cell atlas mapped to a continuous tissue axis
A spatial human thymus cell atlas mapped to a continuous tissue axis
IRF2 is required for development and functional maturation of human NK cells
The RNA Atlas expands the catalog of human non-coding RNAs
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation
Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation
A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-Cell Lymphoma
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia