Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, T-cell and B-cell Immunology, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses.
Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells
Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes
A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells
Separation of Activated T Cells Using Multidimensional Double Spiral (MDDS) Inertial Microfluidics for High-Efficiency CAR T Cell Manufacturing
The T cell receptor sequence influences the likelihood of T cell memory formation
Polymorphic residues in HLA-B that mediate HIV control distinctly modulate peptide interactions with both TCR and KIR molecules
High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening
Machine learning model interpretations explain T cell receptor binding
Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
Antigen identification and high-throughput interaction mapping by reprogramming viral entry
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains
An unbiased characterization of the HLA-E and CD94/NKG2x peptide repertoire reveals peptide ligands that skew NK cell activation
A high-throughput yeast display approach to profile pathogen proteomes for MHC-II binding
Decoupled neoantigen cross-presentation in tumors with high intratumor heterogeneity reduces dendritic cell activation to limit anti-tumor immunity
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide
Rapid assessment of T-cell receptor specificity of the immune repertoire
HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV
Vaccination reshapes the virus-specific T cell repertoire in unexposed adults
Machine learning optimization of peptides for presentation by class II MHCs
Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction
Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
Machine learning optimization of peptides for presentation by class II MHCs
Antibody complementarity determining region design using high-capacity machine learning
IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development
Casting a wider net: Immunosurveillance by nonclassical MHC molecules
Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding