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Patricia L. Opresko

UPMC Hillman Cancer Center · US
Area of research
Molecular Biology · Physiology
Research interest
Research interests include Telomeres, Telomerase, and Senescence, DNA Repair Mechanisms, Advanced biosensing and bioanalysis techniques, and PARP inhibition in cancer therapy.
h-index
48
citations
8,419
works
166
NIH funding
—
primary concept
—
email
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Recent publications

Deregulated DNA ADP-ribosylation impairs telomere replication
Nature Structural & Molecular Biology 2024cited by 22position: middledoi
Premature aging is associated with higher levels of 8‐oxoguanine and increased <scp>DNA</scp> damage in the Polg mutator mouse
Aging Cell 2022cited by 34position: middledoi
Vectorial folding of telomere overhang promotes higher accessibility
Nucleic Acids Research 2022cited by 10position: middledoi
Oxidative guanine base damage regulates human telomerase activity
Nature Structural & Molecular Biology 2016cited by 175position: lastdoi
Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA–DNA pairing
Nucleic Acids Research 2016cited by 32position: middledoi
Human RecQ Helicases in DNA Repair, Recombination, and Replication
Annual Review of Biochemistry 2014cited by 549position: middledoi
Educational attainment and late life telomere length in the Health, Aging and Body Composition Study
Brain Behavior and Immunity 2012cited by 111position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sua Myong · Harvard University2 papers (2016–2022)— · 1 papers (2024–2024)Justin D Lormand · North Carolina State University1 papers (2016–2016)Parminder Kaur · North Carolina State University1 papers (2016–2016)Hui-Ting Lee · University of Alabama at Birmingham1 papers (2016–2016)Deborah L. Croteau · National Human Genome Research Institute1 papers (2014–2014)Ivan Ahel · University of Manchester1 papers (2024–2024)Preston Countryman · North Carolina State University1 papers (2016–2016)Sabine Mai · Guangzhou University of Chinese Medicine1 papers (2022–2022)Hai Pan · North Carolina State University1 papers (2016–2016)Robert W. Sobol · Brown University1 papers (2016–2016)Elissa S. Epel · University of California, San Francisco1 papers (2012–2012)Jaewon Min · Columbia University1 papers (2024–2024)Roderick J. O’Sullivan · UPMC Hillman Cancer Center1 papers (2024–2024)Anne R. Wondisford · UPMC Hillman Cancer Center1 papers (2024–2024)— · 1 papers (2016–2016)Changjiang You · North Carolina State University1 papers (2016–2016)Taosheng Huang · New York University1 papers (2022–2022)Ryan Barnes · Pennsylvania State University1 papers (2022–2022)— · 1 papers (2022–2022)