Area of research
Immunology · Virology
Research interest
Research interests include HIV Research and Treatment, HIV-related health complications and treatments, Immune Cell Function and Interaction, and Galectins and Cancer Biology.
Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain
Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids
Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions
Retro‐age: A unique epigenetic biomarker of aging captured by <scp>DNA</scp> methylation states of retroelements
The single-cell opioid responses in the context of HIV (SCORCH) consortium
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data
Human galectin-9 potently enhances SARS-CoV-2 replication and inflammation in airway epithelial cells
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue
Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons
Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART
Neurocognitive impact of Zika virus infection in adult rhesus macaques
Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19
Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress
Caspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID
Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14
Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease
Prognostic Utility of Right Ventricular Remodeling Over Conventional Risk Stratification in Patients With COVID-19
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research
Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1–infected individuals
Resting-state connectivity and spontaneous activity of ventromedial prefrontal cortex predict depressive symptomology and peripheral inflammation in HIV
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8 <sup>+</sup> T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression
Galectin-9 Is Rapidly Released During Acute HIV-1 Infection and Remains Sustained at High Levels Despite Viral Suppression Even in Elite Controllers
LINE-1 Retrotransposable Element DNA Accumulates in HIV-1-Infected Cells