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Bregje W.M. van Bon

Radboud University Nijmegen · NL
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genomic variations and chromosomal abnormalities, Genetics and Neurodevelopmental Disorders, Genomics and Rare Diseases, and Congenital heart defects research.
h-index
53
citations
13,086
works
140
NIH funding
primary concept
email

Recent publications

Comprehensive EHMT1 variants analysis broadens genotype-phenotype associations and molecular mechanisms in Kleefstra syndrome
The American Journal of Human Genetics 2024cited by 20position: middledoi
ARID1B-related disorder in 87 adults: Natural history and self-sustainability
Genetics in Medicine Open 2024cited by 6position: middledoi
PhenoScore quantifies phenotypic variation for rare genetic diseases by combining facial analysis with other clinical features using a machine-learning framework
Nature Genetics 2023cited by 72position: middledoi
CERT1 mutations perturb human development by disrupting sphingolipid homeostasis
Journal of Clinical Investigation 2023cited by 42position: middledoi
The <i>MAP3K7</i> gene: Further delineation of clinical characteristics and genotype/phenotype correlations
Human Mutation 2022cited by 15position: middledoi
SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females
The American Journal of Human Genetics 2021cited by 89position: middledoi
DLG4-related synaptopathy: a new rare brain disorder
Genetics in Medicine 2021cited by 52position: middledoi
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology
Nature Communications 2021cited by 25position: middledoi
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
Nature Communications 2019cited by 62position: middledoi
Deleterious Variation in BRSK2 Associates with a Neurodevelopmental Disorder
The American Journal of Human Genetics 2019cited by 28position: middledoi
Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations
Neuron 2018cited by 67position: middledoi
De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability
The American Journal of Human Genetics 2017cited by 200position: middledoi
YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction
The American Journal of Human Genetics 2017cited by 169position: middledoi
WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome
The American Journal of Human Genetics 2017cited by 115position: middledoi
A genotype-first approach identifies an intellectual disability-overweight syndrome caused by PHIP haploinsufficiency
European Journal of Human Genetics 2017cited by 57position: middledoi
DVL3 Alleles Resulting in a −1 Frameshift of the Last Exon Mediate Autosomal-Dominant Robinow Syndrome
The American Journal of Human Genetics 2016cited by 110position: middledoi
De novo loss-of-function mutations in WAC cause a recognizable intellectual disability syndrome and learning deficits in Drosophila
European Journal of Human Genetics 2016cited by 50position: middledoi
Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling
The American Journal of Human Genetics 2015cited by 336position: middledoi
Whole-exome sequencing points to considerable genetic heterogeneity of cerebral palsy
Molecular Psychiatry 2015cited by 238position: middledoi
Disruptive de novo mutations of DYRK1A lead to a syndromic form of autism and ID
Molecular Psychiatry 2015cited by 207position: firstdoi
DVL1 Frameshift Mutations Clustering in the Penultimate Exon Cause Autosomal-Dominant Robinow Syndrome
The American Journal of Human Genetics 2015cited by 139position: middledoi
Refining analyses of copy number variation identifies specific genes associated with developmental delay
Nature Genetics 2014cited by 751position: middledoi
Baraitser–Winter cerebrofrontofacial syndrome: delineation of the spectrum in 42 cases
European Journal of Human Genetics 2014cited by 173position: middledoi
Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations
European Journal of Human Genetics 2014cited by 100position: middledoi
Mutations Affecting the SAND Domain of DEAF1 Cause Intellectual Disability with Severe Speech Impairment and Behavioral Problems
The American Journal of Human Genetics 2014cited by 67position: middledoi
Coffin-Siris Syndrome and the BAF Complex: Genotype-Phenotype Study in 63 Patients
Human Mutation 2013cited by 219position: middledoi
<i><scp>MLL2</scp></i> mutation detection in 86 patients with Kabuki syndrome: a genotype–phenotype study
Clinical Genetics 2013cited by 103position: middledoi
Reciprocal deletion and duplication at 2q23.1 indicates a role for MBD5 in autism spectrum disorder
European Journal of Human Genetics 2013cited by 86position: middledoi
Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability
New England Journal of Medicine 2012cited by 1,574position: middledoi
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome
Nature Genetics 2012cited by 306position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Han G. Brunner · Radboud University Nijmegen4 papers (2012–2016)Shalini N. Jhangiani · Baylor College of Medicine3 papers (2015–2016)Alexander Hoischen · University of Groningen3 papers (2012–2016)Donna M. Muzny · Baylor College of Medicine3 papers (2015–2016)Marjolein H. Willemsen · Radboud University Nijmegen3 papers (2012–2015)Richard A. Gibbs · Baylor College of Medicine3 papers (2015–2016)James R. Lupski · The University of Texas Southwestern Medical Center2 papers (2015–2016)Jozef Gécz · SA Health2 papers (2015–2015)Janson J. White · Baylor College of Medicine2 papers (2015–2016) · 2 papers (2015–2016)V. Reid Sutton · Edith Cowan University2 papers (2015–2016)Bert B.A. de Vries · John F. Kennedy University2 papers (2012–2015)Helger G. Yntema · Radboud Institute for Molecular Life Sciences2 papers (2012–2014)Claudia M.B. Carvalho · Broad Institute2 papers (2015–2016)Tjitske Kleefstra · University of Bonn2 papers (2012–2014)Anneke T. Vulto-van Silfhout · Radboud University Nijmegen2 papers (2012–2015)Marloes Steehouwer · Radboud University Nijmegen2 papers (2015–2016)Michelle L. Thompson · Albert Einstein College of Medicine1 papers (2019–2019) · 1 papers (2014–2014) · 1 papers (2014–2014)