Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Single-cell and spatial transcriptomics, Cancer Genomics and Diagnostics, Renal cell carcinoma treatment, and Cancer Immunotherapy and Biomarkers.
The Curated Cancer Cell Atlas provides a comprehensive characterization of tumors at single-cell resolution
Integrative spatial analysis reveals a multi-layered organization of glioblastoma
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma
Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma
HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity