Area of research
Electrical and Electronic Engineering · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Prion Diseases and Protein Misfolding, Alzheimer's disease research and treatments, and Semiconductor Lasers and Optical Devices.
Spatial transcriptomics reveals human cortical layer and area specification
Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy
Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes
Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer’s disease microglia
Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease
Enrichment of somatic cancer driver mutations in Alzheimer’s disease microglia and its association with neuroinflammation
Somatic genomic changes in single Alzheimer’s disease neurons
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity
Somatic mosaicism reveals clonal distributions of neocortical development
Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders
Brain Somatic Mutation in Aging and Alzheimer's Disease
MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations
APP gene copy number changes reflect exogenous contamination
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
Pathogenic Germline Variants in 10,389 Adult Cancers
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
Genotype-guided tacrolimus dosing in African-American kidney transplant recipients
Cofactor Molecules Induce Structural Transformation during Infectious Prion Formation
The N-Terminal, Polybasic Region of PrPC Dictates the Efficiency of Prion Propagation by Binding to PrPSc
AGEP FC-PAM: Alliance for Relevant and Inclusive Sponsorship of Engineering Researchers (ARISE) to Increase the Diversity of the Biomedical Engineering Faculty
EAGER: Topological Optimization Methods for Designing Patient-Specific Large Craniofacial Segmental Bone Replacements
Probing Extreme Physics Through Analysis of Neutron Star Surface Emission
SBIR Phase I: Ultra-miniature in vivo pressure and temperature transducer
STTR Phase I: Miniature Biosensor Utilizing Nanomaterial Coatings
Understanding High-Density Matter Through Analysis of X-ray Bursts
STTR Phase I: Control of the Nanostructure of Organic Photovoltaic Films by Interdiffusion
STTR Phase I: Novel Thin Film Electric Field Tunable Microwave Devices
STTR Phase I: Electrochromic Devices Fabricated from Self-Assembled Polyelectrolytes for Flat Panel Displays
SBIR Phase I: Endohedral Metallofullerenes for Fiber Optic Applications
Mathematical/Computational Tools for Mapping Brain Data Bases
Mathematical/Computational Tools for Mapping Brain Data Bases
International Postdoctoral Fellows Program: Species Assemblages of Leptocephali in the South Pacific
Engineering Creativity Award: Maximum Likelihood Applied to Spectrum Estimation
Nonlinear Dynamics of the Driven Sine-Gordon Chain and Related Models (Materials Research)
Presidential Young Investigator Award
Role of Zooplankton Grazing in Determining Algal Composition in Arctic Lakes: a Component of Alps
Role of Grazers in Determining Algal Composition, Arctic Lake Process Studies (Alps)
Collaborative Research on Dynamics and Ecological Role of Sestonic Detritus in Alaskan Arctic Lakes
Dynamics and Ecological Role of Sestonic Detritus in Alaskan Artic Lakes
Production and Decomposition of Dissolved and Particulate Organic Carbon in Arctic Coastal Ponds