Area of research
Biochemistry · Spectroscopy
Research interest
Research interests include Chemistry, Fluorescence, In vivo, Materials science, Nanoprobe, and Autophagy.
A Smart Visualized Phototherapy Switch: From NIR‐I Imaging‐Guided Photodynamic Therapy to NIR‐II‐Guided Photothermal Therapy for Enhanced Cascade Tumor Photoablation
PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation
Probing Deep Hydrogen Polysulfides Fluctuations In Vivo by Engineering Activatable Fluorescence Reporters with Second Near-Infrared Window Emission
Discovery of autophagy-tethering compounds as potent NLRP3 degraders for IBD Immunotherapy
Design, Synthesis, and Bioevaluation of Novel NLRP3 Inhibitor with IBD Immunotherapy from the Virtual Screen
A dual-modality hydrogen sulfide-specific probe integrating chemiluminescence with NIR fluorescence for targeted cancer imaging
Targeted Degradation of PCSK9 In Vivo by Autophagy-Tethering Compounds
Molecular Engineering of Luminogens for High-Integrity Imaging of Hydrogen Polysulfides via Activatable Aggregation-Induced Dual-Color Fluorescence
Alkaline Phosphatase-Initiated Sensitive Responsiveness of Activatable Probes to Hydrogen Sulfide for Accurate Cancer Imaging and Differentiation
Real-Time Monitoring Renal Impairment Due to Drug-Induced AKI and Diabetes-Caused CKD Using an NAG-Activatable NIR-II Nanoprobe
Aggregation Enhanced Responsiveness of Rationally Designed Probes to Hydrogen Sulfide for Targeted Cancer Imaging
Imaging of ovarian cancers using enzyme activatable probes with second near-infrared window emission
<i>In Vivo</i> Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe
A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging
Realizing highly chemoselective detection of H2S in vitro and in vivo with fluorescent probes inside core-shell silica nanoparticles
Photoacoustic probes for real-time tracking of endogenous H<sub>2</sub>S in living mice
Novel Angiogenic Activity and Molecular Mechanisms of ZYZ-803, a Slow-Releasing Hydrogen Sulfide–Nitric Oxide Hybrid Molecule
A near-infrared fluorescent probe for monitoring fluvastatin-stimulated endogenous H 2 S production
The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification