Area of research
Immunology · Hematology
Research interest
Research interests include Hematopoietic Stem Cell Transplantation, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and IL-33, ST2, and ILC Pathways.
Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage
A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury
A phase 2 study of interleukin-22 and systemic corticosteroids as initial treatment for acute GVHD of the lower GI tract
Challenges and opportunities targeting mechanisms of epithelial injury and recovery in acute intestinal graft-versus-host disease
National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report
The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
Off-the-shelf EBV-specific T cell immunotherapy for rituximab-refractory EBV-associated lymphoma following transplantation
T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage
T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance
RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury
Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease
Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens
High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation
Nrf2 regulates haematopoietic stem cell function
Graft-versus-Host Disease after Double-Unit Cord Blood Transplantation Has Unique Features and an Association with Engrafting Unit-to-Recipient HLA Match
Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation
Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
Interleukin-22 Drives Endogenous Thymic Regeneration in Mice
Extrathymic development of murine T cells after bone marrow transplantation