Area of research
Pathology and Forensic Medicine · Cancer Research
Research interest
Research interests include Lymphoma Diagnosis and Treatment, Cancer Genomics and Diagnostics, CNS Lymphoma Diagnosis and Treatment, and Viral-associated cancers and disorders.
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
Tumor-microenvironment and molecular biology of classic Hodgkin lymphoma in children, adolescents, and young adults
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
An immunohistochemical atlas of necroptotic pathway expression
Targeting latent viral infection in EBV-associated lymphomas
Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression
Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells
Diagnosis and management of Hodgkin lymphoma in children, adolescents, and young adults
Brentuximab vedotin after autologous transplantation in pediatric patients with relapsed/refractory Hodgkin lymphoma
Methionine metabolism controls the B cell EBV epigenome and viral latency
A genetically distinct pediatric subtype of primary CNS large B-cell lymphoma is associated with favorable clinical outcome
Therapeutic options for CTLA-4 insufficiency
MYC Controls the Epstein-Barr Virus Lytic Switch
DNA methylation enzymes and PRC1 restrict B-cell Epstein–Barr virus oncoprotein expression
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy
Phase I Study of the Novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor GSK2816126 in Patients with Advanced Hematologic and Solid Tumors
Primary central nervous system lymphoma: initial features, outcome, and late effects in 75 children and adolescents
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects
Enhancer of zeste homolog 2 (EZH2) inhibitors
Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers
Ibrutinib significantly inhibited Bruton’s tyrosine kinase (BTK) phosphorylation,<i>in-vitro</i> proliferation and enhanced overall survival in a preclinical Burkitt lymphoma (BL) model
Outcomes of adults and children with primary mediastinal B‐cell lymphoma treated with dose‐adjusted <scp>EPOCH</scp>‐R
Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma
Current approaches in the management of low risk Hodgkin lymphoma in children and adolescents
Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells
Rituximab pharmacokinetics in children and adolescents with <i>de novo</i> intermediate and advanced mature B‐cell lymphoma/leukaemia: a Children's Oncology Group report
Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes