Area of research
Physiology · Immunology
Research interest
Research interests include Nitric Oxide and Endothelin Effects, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Cell Adhesion Molecules Research, and Receptor Mechanisms and Signaling.
Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19.
Polymerase delta-interacting protein 2 mediates brain vascular permeability by regulating ROS-mediated ZO-1 phosphorylation and localization at the interendothelial border
Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation.
<b>β</b>1- and <b>β</b>2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation.
Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation
Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction.
Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting.
<b>β</b>1- and <b>β</b>2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation
Correction: Platelet-derived growth factor (PDGF) regulates slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.
Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy.
Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome
Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome.
Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21.
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells.
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer
NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion
Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain
Polymerase δ-interacting Protein 2: A Multifunctional Protein
Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis
Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization
Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts
Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension
Polymerase Delta Interacting Protein 2 Sustains Vascular Structure and Function
Transforming Growth Factor β Inhibits Platelet Derived Growth Factor-Induced Vascular Smooth Muscle Cell Proliferation via Akt-Independent, Smad-Mediated Cyclin D1 Downregulation
Coronary heart disease alters intercellular communication by modifying microparticle‐mediated microRNA transport
Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System
Role of Coronin 1B in PDGF-Induced Migration of Vascular Smooth Muscle Cells