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Bolesław Lach

McMaster University · CA
Area of research
Genetics · Cancer Research
Research interest
Research interests include Medulloblastoma, Biology, Sonic hedgehog, Cancer research, Wnt signaling pathway, and PTCH1.
h-index
citations
3,983
works
16
NIH funding
primary concept
email

Recent publications

ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Nature Genetics 2025cited by 11position: middledoi
Failure of human rhombic lip differentiation underlies medulloblastoma formation
Nature 2022cited by 157position: middledoi
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation
Nature 2022cited by 4position: middledoi
The transcriptional landscape of Shh medulloblastoma
Nature Communications 2021cited by 94position: middledoi
Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma
Cell Reports Medicine 2020cited by 48position: middledoi
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma
Nature 2019cited by 172position: middledoi
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma
Developmental Cell 2018cited by 45position: middledoi
Intertumoral Heterogeneity within Medulloblastoma Subgroups
Cancer Cell 2017cited by 1,246position: middledoi
Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype
Clinical Cancer Research 2015cited by 48position: middledoi
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
Nature 2014cited by 621position: middledoi
Cytogenetic Prognostication Within Medulloblastoma Subgroups
Journal of Clinical Oncology 2014cited by 313position: middledoi
WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
Acta Neuropathologica Communications 2014cited by 47position: middledoi
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
Acta Neuropathologica 2013cited by 167position: middledoi
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Nature 2012cited by 918position: middledoi
Differences Between the Pattern of Developmental Abnormalities in Autism Associated With Duplications 15q11.2-q13 and Idiopathic Autism
Journal of Neuropathology & Experimental Neurology 2012cited by 92position: middledoi
Abstract 1428: A CpG island methylator phenotype defines a clinically aggressive subgroup of posterior fossa ependymoma
Cancer Research 2012cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Edwin H. Cook · University of Illinois Chicago1 papers (2012–2012)Timothy Van Meter · Virginia Commonwealth University1 papers (2012–2012) · 1 papers (2012–2012)David Shih · University of Hong Kong1 papers (2012–2012)Gary D. Bader · University of Waterloo1 papers (2012–2012)Lynette Lau · Hospital for Sick Children1 papers (2012–2012)Jarek Wegiel · New York University1 papers (2012–2012)Livia Garzia · McGill University Health Centre1 papers (2012–2012)N. Carolyn Schanen · University of Illinois Chicago1 papers (2012–2012)Kelsey C. Bertrand · St. Jude Children's Research Hospital1 papers (2012–2012)Stephen S. Roberts · McGill University1 papers (2012–2012)Adrian M. Dubuc · Harvard University1 papers (2012–2012) · 1 papers (2012–2012)Andrey Korshunov · German Cancer Research Center1 papers (2012–2012)Krzysztof Nowicki · California Institute for Regenerative Medicine1 papers (2012–2012)Stefan M. Pfister · Université du Québec1 papers (2012–2012) · 1 papers (2012–2012) · 1 papers (2012–2012)Paul A. Northcott · Children's Research Hospital1 papers (2012–2012) · 1 papers (2012–2012)