Area of research
Infectious Diseases · Virology
Research interest
Research interests include COVID-19 Clinical Research Studies, HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, and interferon and immune responses.
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution
Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19
Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters
90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization
Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression
The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication
Nonproductive exposure of PBMCs to SARS‐CoV‐2 induces cell‐intrinsic innate immune responses
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
Mild COVID-19 despite autoantibodies against type I IFNs in autoimmune polyendocrine syndrome type 1
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19
A realistic transfer method reveals low risk of SARS-CoV-2 transmission via contaminated euro coins and banknotes
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression
Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
Absence of cGAS-mediated type I IFN responses in HIV-1–infected T cells
Delayed viral clearance and exacerbated airway hyperinflammation in hypertensive COVID-19 patients
Labyrinthopeptins Exert Broad-Spectrum Antiviral Activity through Lipid-Binding-Mediated Virolysis
Quantitative Proteomics of Uukuniemi Virus-host Cell Interactions Reveals GBF1 as Proviral Host Factor for Phleboviruses
Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites
Interferon‐inducible cholesterol‐25‐hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation