Area of research
Hematology · Immunology
Research interest
Research interests include Acute Myeloid Leukemia Research, Immune Cell Function and Interaction, CAR-T cell therapy research, and Chronic Lymphocytic Leukemia Research.
Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery.
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
TIM3 blockade with hypomethylating therapy restores NK and cytotoxic CD4+ T cell activity in patients with AML or MDS
Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses.
Somatic mutations associate with clonal expansion of CD8<sup>+</sup> T cells.
Understanding human health through metatranscriptomics
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics
Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine
Identification of DHX40 as a candidate susceptibility gene for colorectal and hematological neoplasia.
Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia
Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8<sup>+</sup> T-cell large granular lymphocytic leukemia.
T and NK cell abundance defines two distinct subgroups of renal cell carcinoma.
Epigenetic modifier gene mutations in chronic myeloid leukemia (CML) at diagnosis are associated with risk of relapse upon treatment discontinuation.
A novel partial de novo duplication of JARID2 gene causing a neurodevelopmental phenotype.
Single-cell functional genomics of natural killer cell evasion in blood cancers
A novel partial de novo duplication of JARID2 gene causing a neurodevelopmental phenotype
Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia
Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia.
Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets.
RUNX1 mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses.
STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation.
Cancer-Associated Fibroblasts Modulate Transcriptional Signatures Involved in Proliferation, Differentiation and Metastasis in Head and Neck Squamous Cell Carcinoma.
CD73 contributes to anti-inflammatory properties of afferent lymphatic endothelial cells in humans and mice.
Comparison of Structural and Short Variants Detected by Linked-Read and Whole-Exome Sequencing in Multiple Myeloma.
Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity.
Immunogenomic Landscape of Hematological Malignancies.
Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy.
Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia.
Genomics of asthma, allergy and chronic rhinosinusitis: novel concepts and relevance in airway mucosa
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease.