Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Melanoma and MAPK Pathways, melanin and skin pigmentation, Skin Protection and Aging, and Protease and Inhibitor Mechanisms.
Exploiting Paradoxical Activation of Oncogenic MAPK Signaling by Targeting Mitochondria to Sensitize <i>NRAS</i> Mutant-Melanoma to Vemurafenib.
Differential impacts of nickel toxicity: NiO and NiSO4 on skin health and barrier function
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid.
Evaluation of the photoprotective and antioxidant potential of an avobenzone derivative.
Peroxiredoxin-2 represses NRAS-mutated melanoma cells invasion by modulating EMT markers.
Modeling Melanoma Heterogeneity In Vitro: Redox, Resistance and Pigmentation Profiles.
MITF, TFEB and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma
Brazilian National Network of Alternative Methods (RENAMA) 10th Anniversary: Meeting of the Associated Laboratories, May 2022.
Tissue Engineering Challenges for Cultivated Meat to Meet the Real Demand of a Global Market.
Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.
2-Methoxyestradiol-3,17-O,O-bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells
Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes.
Redox-Related Proteins in Melanoma Progression.
Kynurenine inhibits melanogenesis in human melanocyte-keratinocyte co-cultures and in a reconstructed 3D skin model.
Upregulation of the novel lncRNA U731166 is associated with migration, invasion and vemurafenib resistance in melanoma.
<i>Pouteria macrophylla</i> Fruit Extract Microemulsion for Cutaneous Depigmentation: Evaluation Using a 3D Pigmented Skin Model.
Mesenchymal stem cells express epidermal markers in an <i>in vitro</i> reconstructed human skin model.
3-Bromopyruvate Suppresses the Malignant Phenotype of Vemurafenib-Resistant Melanoma Cells.
Quercetin increases mitochondrial proteins (VDAC and SDH) and downmodulates AXL and PIM-1 tyrosine kinase receptors in NRAS melanoma cells.
Glutamic acid promotes hair growth in mice.
Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn's Disease.
Immunotoxic mechanisms of cigarette smoke and heat-not-burn tobacco vapor on Jurkat T cell functions.
In Vitro Evaluation of the Photoprotective Potential of Quinolinic Alkaloids Isolated from the Antarctic Marine Fungus Penicillium echinulatum for Topical Use.
Nanostructured lipid carriers enhances the safety profile of tretinoin: <i>in vitro</i> and healthy human volunteers' studies.
Anhydroecgonine methyl ester, a cocaine pyrolysis product, contributes to cocaine-induced rat primary hippocampal neuronal death in a synergistic and time-dependent manner.
Skin Equivalent Models: Protocols for In Vitro Reconstruction for Dermal Toxicity Evaluation.
Xanthan gum-based hydrogel containing nanocapsules for cutaneous diphenyl diselenide delivery in melanoma therapy.
Fucoxanthin for Topical Administration, a Phototoxic vs. Photoprotective Potential in a Tiered Strategy Assessed by In Vitro Methods.
Air Particulate Matter Induces Skin Barrier Dysfunction and Water Transport Alteration on a Reconstructed Human Epidermis Model.
Targeting mitochondria in melanoma: Interplay between MAPK signaling pathway and mitochondrial dynamics.