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Michael U. Callaghan

Agios Pharmaceuticals (United States) · US
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Area of research
Hematology · Genetics
Research interest
Research interests include Hemophilia Treatment and Research, Hemoglobinopathies and Related Disorders, Platelet Disorders and Treatments, and Iron Metabolism and Disorders.
h-index
30
citations
5,087
works
151
NIH funding
primary concept
Medicine
email

Recent publications

Global Seroprevalence of Pre-existing Immunity Against AAV5 and Other AAV Serotypes in People with Hemophilia A
Human Gene Therapy 2022cited by 105position: middledoi
Consensus definition of essential, optimal, and suggested components of a pediatric sickle cell disease center
Pediatric Blood & Cancer 2022cited by 19position: middledoi
Clinical predictors of poor outcomes in patients with sickle cell disease and COVID-19 infection
Blood Advances 2021cited by 78position: middledoi
The effect of emicizumab prophylaxis on long‐term, self‐reported physical health in persons with haemophilia A without factor VIII inhibitors in the HAVEN 3 and HAVEN 4 studies
Haemophilia 2021cited by 56position: middledoi
Development and testing of the Satisfaction Questionnaire with Intravenous or Subcutaneous Hemophilia Injection and results from the Phase 3 HAVEN 3 study of emicizumab prophylaxis in persons with haemophilia A without FVIII inhibitors
Haemophilia 2021cited by 23position: middledoi
Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies
Blood 2020cited by 284position: firstdoi
Pharmacokinetics and Pharmacodynamics of Emicizumab in Persons with Hemophilia A with Factor VIII Inhibitors: HAVEN 1 Study
Thrombosis and Haemostasis 2020cited by 96position: middledoi
Discussing investigational AAV gene therapy with hemophilia patients: A guide
Blood Reviews 2020cited by 53position: middledoi
ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes
JCI Insight 2020cited by 24position: middledoi
Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma
Journal of Clinical Medicine 2019cited by 44position: middledoi
Novel therapeutics for hemophilia and other bleeding disorders
Blood 2018cited by 54position: firstdoi
Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial)
Blood Advances 2018cited by 37position: middledoi
Emicizumab Prophylaxis in Hemophilia A with Inhibitors
New England Journal of Medicine 2017cited by 1,075position: middledoi
Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR
Oncotarget 2017cited by 51position: middledoi
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia
Nature Genetics 2015cited by 326position: middledoi
Induction of BCL2-Interacting Killer, BIK, is Mediated for Anti-Cancer Activity of Curcumin in Human Head and Neck Squamous Cell Carcinoma Cells
Journal of Cancer 2015cited by 29position: middledoi
SMAD4 is a potential prognostic marker in human breast carcinomas
Tumor Biology 2013cited by 21position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Steven W. Pipe · Amsterdam UMC Location Vrije Universiteit Amsterdam4 papers (2018–2021)Andrew M. Fribley · University of Alabama at Birmingham4 papers (2013–2019)Johnny Mahlangu · National Health Laboratory Service4 papers (2017–2021)Claude Négrier · Université Claude Bernard Lyon 14 papers (2017–2021)Gallia G. Levy · Atotech (United States)4 papers (2017–2021)Guy Young · University of Southern California3 papers (2017–2020)Markus Niggli · Roche (Switzerland)3 papers (2020–2021)Midori Shima · Nara Medical University3 papers (2017–2021)Christophe Schmitt · Roche (Switzerland)3 papers (2017–2020)Ido Paz‐Priel · Gilead Sciences (United States)3 papers (2020–2021)Johannes Oldenburg · 657 Oslo3 papers (2017–2021)Qinghua Zeng · University of Alabama at Birmingham3 papers (2013–2019)Yue Xi · South China Agricultural University3 papers (2013–2019)Deepa Manwani · Albert Einstein College of Medicine2 papers (2021–2022)Ofelia Álvarez · University of Miami2 papers (2018–2022)Sammy Chebon · Suva2 papers (2020–2021) · 2 papers (2021–2021)Danielle M. Garshott · University of California San Diego2 papers (2015–2019)Víctor Jiménez‐Yuste · Hospital Universitario La Paz2 papers (2020–2021)Julie Kanter · University of Alabama at Birmingham2 papers (2018–2022)
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