Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Nuclear Structure and Function, RNA Research and Splicing, Cellular Mechanics and Interactions, and Genomics and Chromatin Dynamics.
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer
Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
Nuclear envelope rupture and repair during cancer cell migration
A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration
Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments
Nuclear Mechanics and Mechanotransduction in Health and Disease
Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling