Area of research
Molecular Biology · Oncology
Research interest
Research interests include Redox biology and oxidative stress, Glutathione Transferases and Polymorphisms, Genomics, phytochemicals, and oxidative stress, and Cancer-related Molecular Pathways.
p53 as a hub in cellular redox regulation and therapeutic target in cancer
TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy
Targeting mutant p53 for efficient cancer therapy
Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver
ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis
Sepp1UF forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1
A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification