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Cara Mathews

Mass General Brigham · US
Area of research
Obstetrics and Gynecology · Reproductive Medicine
Research interest
Research interests include Endometrial and Cervical Cancer Treatments, Ovarian cancer diagnosis and treatment, PARP inhibition in cancer therapy, and Genetic factors in colorectal cancer.
h-index
35
citations
8,632
works
242
NIH funding
primary concept
Medicine
email

Recent publications

First-In-Human Trial of Encapsulated Cells Constitutively Expressing Localized IL-2 in Patients with High-Grade Serous Ovarian Carcinoma.
2026cited by 0position: contributordoi
Neoadjuvant or concurrent atezolizumab with chemoradiation for locally advanced cervical cancer: a randomized phase I trial
Nature Communications 2025cited by 15position: middledoi
Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers
npj Precision Oncology 2025cited by 15position: middledoi
Neoadjuvant or concurrent atezolizumab with chemoradiation for locally advanced cervical cancer: a randomized phase I trial.
2025cited by 11position: contributordoi
Quality-adjusted time without symptoms of disease progression or toxicity of treatment in patients with primary advanced or recurrent endometrial cancer treated with dostarlimab plus carboplatin-paclitaxel versus carboplatin-paclitaxel
International Journal of Gynecological Cancer 2025cited by 1position: middledoi
The efficacy and safety of mirvetuximab soravtansine in FRα-positive, third-line and later, recurrent platinum-sensitive ovarian cancer: the single-arm phase II PICCOLO trial
Annals of Oncology 2024cited by 35position: middledoi
Final results of BrUOG 354: A randomized phase II trial of nivolumab alone or in combination with ipilimumab for people with ovarian and other extra-renal clear cell carcinomas.
Journal of Clinical Oncology 2024cited by 26position: middledoi
Normal Risk Ovarian Screening Study: 21-Year Update
Journal of Clinical Oncology 2024cited by 15position: middledoi
Phase I and Randomized Phase II Study of Ruxolitinib With Frontline Neoadjuvant Therapy in Advanced Ovarian Cancer: An NRG Oncology Group Study.
2024cited by 15position: contributordoi
Normal Risk Ovarian Screening Study: 21-Year Update.
2024cited by 12position: contributordoi
Overall survival and progression-free survival by PD-L1 status among endometrial cancer patients treated with pembrolizumab plus carboplatin/paclitaxel as compared to carboplatin/paclitaxel plus placebo in the NRG GY018 trial
Gynecologic Oncology 2024cited by 6position: middledoi
Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer
New England Journal of Medicine 2023cited by 671position: middledoi
Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial.
2023cited by 359position: contributordoi
Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial
The Lancet 2023cited by 198position: middledoi
Adjuvant chemotherapy following chemoradiotherapy as primary treatment for locally advanced cervical cancer versus chemoradiotherapy alone (OUTBACK): an international, open-label, randomised, phase 3 trial
The Lancet Oncology 2023cited by 185position: middledoi
Tisotumab Vedotin in Combination With Carboplatin, Pembrolizumab, or Bevacizumab in Recurrent or Metastatic Cervical Cancer: Results From the innovaTV 205/GOG-3024/ENGOT-cx8 Study
Journal of Clinical Oncology 2023cited by 76position: middledoi
Tisotumab Vedotin in Combination With Carboplatin, Pembrolizumab, or Bevacizumab in Recurrent or Metastatic Cervical Cancer: Results From the innovaTV 205/GOG-3024/ENGOT-cx8 Study.
2023cited by 59position: contributordoi
Safety, Efficacy, and Biomarker Analyses of Dostarlimab in Patients with Endometrial Cancer: Interim Results of the Phase I GARNET Study.
2023cited by 52position: contributordoi
LBA43 Updated response data and analysis of progression free survival by mechanism of mismatch repair loss in endometrial cancer (EC) patients (pts) treated with pembrolizumab plus carboplatin/paclitaxel (CP) as compared to CP plus placebo (PBO) in the NRG GY018 trial
Annals of Oncology 2023cited by 19position: middledoi
#267 Quality-adjusted time without symptoms of disease or toxicity in patients with primary advanced or recurrent endometrial cancer treated with dostarlimab plus carboplatin-paclitaxel versus carboplatin-paclitaxel in the ENGOT-EN6/GOG-3031/RUBY trial
International Journal of Gynecological Cancer 2023cited by 2position: middledoi
Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET—a phase I, single-arm study
Journal for ImmunoTherapy of Cancer 2022cited by 314position: middledoi
<i>TP53</i> Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study
Journal of Clinical Oncology 2022cited by 74position: middledoi
<i>TP53</i> Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study.
2022cited by 59position: contributordoi
2022-RA-1198-ESGO Post hoc analysis of objective response rate by mismatch repair protein dimer loss/mutation status in patients with mismatch repair deficient endometrial cancer treated with dostarlimab
International Journal of Gynecological Cancer 2022cited by 7position: middledoi
Adjuvant chemotherapy following chemoradiation as primary treatment for locally advanced cervical cancer compared to chemoradiation alone: The randomized phase III OUTBACK Trial (ANZGOG 0902, RTOG 1174, NRG 0274).
Journal of Clinical Oncology 2021cited by 90position: middledoi
Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study
Gynecologic Oncology 2021cited by 83position: middledoi
Randomized Phase II Trial of Nivolumab Versus Nivolumab and Ipilimumab for Recurrent or Persistent Ovarian Cancer: An NRG Oncology Study
Journal of Clinical Oncology 2020cited by 346position: middledoi
GOG 244 - The Lymphedema and Gynecologic cancer (LeG) study: The impact of lower-extremity lymphedema on quality of life, psychological adjustment, physical disability, and function
Gynecologic Oncology 2020cited by 67position: middledoi
GOG 244-The lymphedema and gynecologic cancer (LEG) study: Incidence and risk factors in newly diagnosed patients
Gynecologic Oncology 2019cited by 125position: middledoi
GOG 244 - The LymphEdema and Gynecologic cancer (LEG) study: The association between the gynecologic cancer lymphedema questionnaire (GCLQ) and lymphedema of the lower extremity (LLE)
Gynecologic Oncology 2019cited by 54position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Carol Aghajanian · AstraZeneca (Italy)8 papers (2018–2025)Heather A. Lankes · NRG Oncology7 papers (2016–2025)Kathleen N. Moore · Oklahoma City University6 papers (2017–2024) · 6 papers (2022–2025)Charles A. Leath · St. Vincent's Birmingham5 papers (2022–2025)Michael W. Sill · NRG Oncology5 papers (2019–2024)Oliver Zivanovic · Gynecologic Oncology Group5 papers (2017–2020)David G. Mutch · Cancer Research Center5 papers (2016–2024)Roisin E. O’Cearbhaill · Maine Farmland Trust4 papers (2023–2025)Joan L. Walker · Cornell University4 papers (2017–2020)Robert S. Mannel · NRG Oncology4 papers (2016–2025)Angeles Alvarez Secord · Duke University4 papers (2016–2024)Ana Oaknin · Universitair Ziekenhuis Leuven4 papers (2018–2023)Floor Backes · Gynecologic Oncology Group3 papers (2016–2024)Bhavana Pothuri · NYU Langone Health3 papers (2022–2023)Lari Wenzel · University of California, Irvine3 papers (2019–2020)Bradley J. Monk · University of Cincinnati Medical Center3 papers (2021–2023)Virginia L. Filiaci · NRG Oncology3 papers (2016–2022)Giovanni Scambia · PromoFirenze3 papers (2018–2023) · 3 papers (2019–2020)