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David M. Langenau

Center for Cancer Research · US
Area of research
Cell Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Zebrafish, Biology, Cancer research, Rhabdomyosarcoma, Cancer, and Medicine.
h-index
citations
2,646
works
19
NIH funding
primary concept
email

Recent publications

The FLRT3-UNC5B Pathway is a Novel Regulator of T Immunosurveillance
The Journal of Immunology 2024cited by 0position: middledoi
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
Nature Cancer 2022cited by 63position: lastdoi
Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials
Nature Reviews Drug Discovery 2021cited by 546position: lastdoi
Zebrafish patient avatars in cancer biology and precision cancer therapy
Nature reviews. Cancer 2020cited by 261position: middledoi
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
Leukemia 2020cited by 26position: lastdoi
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
Nature Communications 2019cited by 329position: middledoi
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish
Cell 2019cited by 259position: lastdoi
tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
eLife 2018cited by 77position: lastdoi
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia
The Journal of Experimental Medicine 2018cited by 30position: middledoi
Identification and characterization of T reg–like cells in zebrafish
The Journal of Experimental Medicine 2017cited by 71position: middledoi
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
Cell Reports 2017cited by 66position: lastdoi
Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors
Zebrafish 2017cited by 4position: middledoi
Clusters of circulating tumor cells traverse capillary-sized vessels
Proceedings of the National Academy of Sciences 2016cited by 493position: middledoi
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
Nature Communications 2016cited by 90position: lastdoi
Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer
Cancer Research 2015cited by 23position: firstdoi
Optimized cell transplantation using adult rag2 mutant zebrafish
Nature Methods 2014cited by 144position: lastdoi
A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development
Development 2013cited by 55position: middledoi
The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish
PLoS ONE 2013cited by 34position: middledoi
Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency
Leukemia 2012cited by 75position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Myron S. Ignatius · The Ohio State University5 papers (2013–2018)Leonard I. Zon · Harvard University5 papers (2013–2021)Riadh Lobbardi · Center for Cancer Research4 papers (2014–2017)Madeline N. Hayes · Hospital for Sick Children4 papers (2016–2022)Qin Tang · University of Electronic Science and Technology of China4 papers (2014–2018)Jessica S. Blackburn · University of Kentucky4 papers (2012–2020)Chuan Yan · National University of Singapore4 papers (2020–2024)John C. Moore · Southern Illinois University Edwardsville3 papers (2014–2016)Karin M. McCarthy · Center for Cancer Research3 papers (2017–2022)Finola E. Moore · Center for Cancer Research3 papers (2014–2018)Eleanor Y. Chen · University of Iowa3 papers (2013–2018)Yariv Houvras · Urologische Klinik München3 papers (2014–2017)Alexander Jin · Center for Cancer Research3 papers (2017–2022)Sara P. Garcia · Centro de Investigación Biomédica en Red de Cáncer3 papers (2018–2022)Maurizio Fazio · Boston Children's Hospital2 papers (2017–2020)Daniel Do · The Ohio State University2 papers (2020–2022)Sarah Martinez · Georgetown University2 papers (2012–2014)Inês M. Tenente · Center for Cancer Research2 papers (2014–2016)Elaine G. Garcia · Center for Cancer Research2 papers (2016–2020)Narie Y. Storer · Harvard Stem Cell Institute2 papers (2013–2013)