Area of research
Immunology · Hematology
Research interest
Research interests include Medicine, Stroke (engine), ADAMTS13, Chemistry, Thrombotic thrombocytopenic purpura, and Thrombolysis.
Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura
Crystal structure and substrate-induced activation of ADAMTS13
ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice
N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura
Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice
Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS‐13