Area of research
Molecular Biology · Ecology
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Advanced biosensing and bioanalysis techniques, and Bacteriophages and microbial interactions.
Naturally ornate RNA-only complexes revealed by cryo-EM
Phage-triggered reverse transcription assembles a toxic repetitive gene from a noncoding RNA
Fine-grained image recognition method for digital media based on feature enhancement strategy
Prokaryotic innate immunity through pattern recognition of conserved viral proteins
UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions
A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy
Diverse enzymatic activities mediate antiviral immunity in prokaryotes
Highly Parallel Profiling of Cas9 Variant Specificity
Computational Identification of Repeat-Containing Proteins and Systems
Engineering of CRISPR-Cas12b for human genome editing
Unexpected connections between type VI-B CRISPR-Cas systems, bacterial natural competence, ubiquitin signaling network and DNA modification through a distinct family of membrane proteins
A highly homogeneous expansion microscopy polymer composed of tetrahedron-like monomers
Engineered CRISPR-Cas9 nuclease with expanded targeting space
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons
Engineered Cpf1 variants with altered PAM specificities
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies
Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies
PMC 2016cited by 6position: middle
Rationally engineered Cas9 nucleases with improved specificity