Area of research
Immunology · Oncology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, Single-cell and spatial transcriptomics, and Monoclonal and Polyclonal Antibodies Research.
Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype
A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance
PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6<sup>high</sup> uterine leiomyosarcoma to PD‐1 blockade
CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours
Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection
Multiomics and spatial mapping characterizes human CD8 <sup>+</sup> T cell states in cancer
Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell–Cell Interactions That Predict Immunotherapy Response
Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level
Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
Multiplexed Immunohistochemistry and Digital Pathology as the Foundation for Next-Generation Pathology in Melanoma: Methodological Comparison and Future Clinical Applications
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model
Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling
Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing
In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy
Computerised scoring protocol for identification and quantification of different immune cell populations in breast tumour regions by the use of QuPath software
Age‐related remodelling of the blood immunological portrait and the local tumor immune response in patients with luminal breast cancer
A Functional Landscape of CKD Entities From Public Transcriptomic Data