Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Biology, Cell biology, China, Nicotinamide adenine dinucleotide phosphate, Library science, and NAD+ kinase.
NADPH acts as an endogenous P2X7 receptor modulator to gate neuroinflammatory responses of microglia
Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophy
Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors
The P2X7 receptor mediates NADPH transport across the plasma membrane
PDK4-dependent hypercatabolism and lactate production of senescent cells promotes cancer malignancy
The Aging Biomarker Consortium represents a new era for aging research in China
Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer
Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis
SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents
<scp>SIRT</scp> 3‐dependent <scp>GOT</scp> 2 acetylation status affects the malate–aspartate <scp>NADH</scp> shuttle activity and pancreatic tumor growth
Regulation of G6PD acetylation by KAT9/SIRT2 modulates NADPH homeostasis and cell survival during oxidative stress