Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Acute Lymphoblastic Leukemia research, Advanced biosensing and bioanalysis techniques, Dendrimers and Hyperbranched Polymers, and RNA Interference and Gene Delivery.
Exploring the gut microbiome and metabolomic interactions of antimetabolite drugs to optimize therapy.
Does Calcium Supplementation Increase Cardiovascular Risk? - A Meta Analysis of Randomized Controlled Trials and Cohort Studies
Quantitative Comparison of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Adults: A Systematic Review and Model-Based Meta-Analysis.
Impact of Methotrexate and 7-Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non-Hodgkin Lymphoma.
Development and Application of an LC-MS/MS Method for Simultaneous Quantification of Azathioprine and Its Metabolites: Pharmacokinetic and Microbial Metabolism Study of a Colon-Targeted Nanoparticle.
Simple and robust analysis of cefuroxime in human plasma and bone tissues by LC-MS/MS.
Push Forward Clinical Management of Hematological Toxicity due to Lenalidomide Overexposure: Model-Informed Precision Dosing for Chinese Population With Renal Insufficiency.
Methotrexate gene polymorphisms link to toxicity but not pharmacokinetics in Chinese adults and adolescents with acute lymphoblastic leukemia
Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis
Modulation of mercaptopurine intestinal toxicity and pharmacokinetics by gut microbiota
Clinical characteristics and pharmacokinetics of PAXLOVID in COVID-19 patients with hematological tumor.
Improved high-performance liquid chromatography tandem mass spectrometry method for quantification of infliximab in pediatric plasma and its application in therapeutic drug monitoring.
Combination of size‐exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma‐derived extracellular vesicles
Effects of time-restricted eating with different eating windows on human metabolic health: pooled analysis of existing cohorts
Identification of combinatorial miRNA panels derived from extracellular vesicles as biomarkers for esophageal squamous cell carcinoma
Cellular Uptake and Transport Mechanism of 6-Mercaptopurine Nanomedicines for Enhanced Oral Bioavailability.
Microbiome changes involves in mercaptopurine mediated anti-inflammatory response in acute lymphoblastic leukemia mice
Comparation of time-course, dose-effect, influencing factors and adverse events of biologics in the treatment of adults with moderate to severe plaque psoriasis
Population pharmacokinetics of ruxolitinib in children with hemophagocytic lymphohistiocytosis: focus on the drug-drug interactions.
Effect of Intravenous Tirofiban vs Placebo Before Endovascular Thrombectomy on Functional Outcomes in Large Vessel Occlusion Stroke
A Systematic Review and Meta-Analysis: <i>Lactobacillus acidophilus</i> for Treating Acute Gastroenteritis in Children.
Review of HPLC-MS methods for the analysis of nicotine and its active metabolite cotinine in various biological matrices.
Association of Corticosteroid Treatment With Outcomes in Pediatric Patients With Bacterial Meningitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Development and application of an LC-MS/MS method for pharmacokinetic study of ruxolitinib in children with hemophagocytic lymphohistiocytosis.
Medication therapy of high‐dose methotrexate: An evidence‐based practice guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society
Preparation, Characterization, Pharmacokinetic, and Therapeutic Potential of Novel 6-Mercaptopurine-Loaded Oral Nanomedicines for Acute Lymphoblastic Leukemia.
Spotlight on eltrombopag in pediatric ITP in China: a long-term observational study in real-world practice.
Associations between the 1438A/G, 102T/C, and rs7997012G/A polymorphisms of HTR2A and the safety and efficacy of antidepressants in depression: a meta-analysis.
Optimization of Busulfan Dosing Regimen in Pediatric Patients Using a Population Pharmacokinetic Model Incorporating GST Mutations.
Quality assessment of clinical guidelines on probiotics therapy in children with IBD using the AGREE II instrument.