Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Tryptophan and brain disorders, and Substance Abuse Treatment and Outcomes.
Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD
Robust inference and widespread genetic correlates from a large-scale genetic association study of human personality
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology
Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood–brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders
Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits
Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction
Alcohol use and risk of dementia in diverse populations
Opioid use disorder and brain health: observational and genetic associations
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
Exploring the genetic overlap between twelve psychiatric disorders
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder
Identification of 64 new risk loci for major depression, refinement of the genetic architecture and risk prediction of recurrence and comorbidities
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program
Genetic contributions to anxiety disorders: where we are and where we are heading
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans
Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci