Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research interests include Reproductive Biology and Fertility, Epigenetics and DNA Methylation, Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities, and Sperm and Testicular Function.
Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson’s disease models
Nucleolar migration regulates meiotic sex chromosome inactivation via phase separation during mammalian spermatogenesis.
SOX9 haploinsufficiency reveals SOX9-Noggin interaction in BMP-SMAD signaling pathway in chondrogenesis.
Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer.
Primate-specific microRNA-1202 regulates dopaminergic neurogenesis by targeting APC2 and modulates WNT/β-catenin signaling pathway in midbrain organoid
Microprotein PLUM encoded by Lin28b uORF is a cytoplasmic determinant of pluripotency and embryonic development.
Human organoids reveal PTEN-driven mesendoderm specification via retinoic acid signaling suppression
NAD<sup>+</sup> dependent UPR<sup>mt</sup> activation underlies intestinal aging caused by mitochondrial DNA mutations.
Biomarker analysis of the ASPEN study comparing zanubrutinib with ibrutinib for patients with Waldenström macroglobulinemia
WRN loss accelerates abnormal adipocyte metabolism in Werner syndrome.
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation.
Pathogenic TDRD12 variants cause defective piRNA pathway and male infertility in humans and mice.
Zanubrutinib Versus Ibrutinib in Symptomatic Waldenström Macroglobulinemia: Final Analysis From the Randomized Phase III ASPEN Study
Neuroprotective Effects of Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Extracellular Vesicles in Ischemic Stroke Models.
RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits.
Deficiency of the <i>Tmem232</i> Gene Causes Male Infertility with Morphological Abnormalities of the Sperm Flagellum in Mice.
Modification of maternally defined H3K4me3 regulates the inviability of interspecific <i>Xenopus</i> hybrids.
Phosphorylation of the CDK Substrate MSCDK Regulates Synaptonemal Complex Disassembly and Meiosis Metaphase I Transition
Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation.
Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation
Plin2-mediated lipid droplet mobilization accelerates exit from pluripotency by lipidomic remodeling and histone acetylation.
WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome.
LRRC46 Accumulates at the Midpiece of Sperm Flagella and Is Essential for Spermiogenesis and Male Fertility in Mouse.
ZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation
ZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation
Pooled safety analysis of zanubrutinib monotherapy in patients with B-cell malignancies
Altered Actinobacteria and Firmicutes Phylum Associated Epitopes in Patients With Parkinson’s Disease
Oral, Nasal, and Gut Microbiota in Parkinson’s Disease
Phase separation drives the self-assembly of mitochondrial nucleoids for transcriptional modulation.