Area of research
Physiology · Cellular and Molecular Neuroscience
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Computational Drug Discovery Methods, and Nanoparticle-Based Drug Delivery.
PRPS2 enhances RNA m6A methylation by stimulating SAM synthesis through enzyme-dependent and independent mechanisms
Self‐Disassembling and Oxygen‐Generating Porphyrin‐Lipoprotein Nanoparticle for Targeted Glioblastoma Resection and Enhanced Photodynamic Therapy
Self-stacked small molecules for ultrasensitive, substrate-free Raman imaging in vivo
Insights into therapeutic peptides in the cancer-immunity cycle: Update and challenges
Self-assembled PROTACs enable protein degradation to reprogram the tumor microenvironment for synergistically enhanced colorectal cancer immunotherapy
Effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section
Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits
Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma
Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1
Tumor Metabolism-Rewriting Nanomedicines for Cancer Immunotherapy
Comparative Proteomics Inspired Self‐Stimulated Release Hydrogel Reinforces the Therapeutic Effects of MSC‐EVs on Alzheimer's Disease
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma
Polymer chimera of stapled oncolytic peptide coupled with anti-PD-L1 peptide boosts immunotherapy of colorectal cancer
Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming
A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA
Multifunctional Anti-Alzheimer’s Disease Effects of Natural Xanthone Derivatives: A Primary Structure-Activity Evaluation
Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse
Targeting Endothelial Cell-Specific Molecule 1 Protein in Cancer: A Promising Therapeutic Approach
The peptide PROTAC modality: a novel strategy for targeted protein ubiquitination
Clearance of two organic nanoparticles from the brain via the paravascular pathway
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance
Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia
Dysregulated Urinary Arginine Metabolism in Older Adults With Amnestic Mild Cognitive Impairment
Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase
Necroptotic cancer cells-mimicry nanovaccine boosts anti-tumor immunity with tailored immune-stimulatory modality
Nanoparticles Coated with Neutrophil Membranes Can Effectively Treat Cancer Metastasis
Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
Nanoformulated alpha-mangostin ameliorates Alzheimer's disease neuropathology by elevating LDLR expression and accelerating amyloid-beta clearance