Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Congenital heart defects research, Pluripotent Stem Cells Research, Zebrafish Biomedical Research Applications, and Epigenetics and DNA Methylation.
Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm
ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation
SARS-CoV-2 infection causes dopaminergic neuron senescence
Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection
Author Correction: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection
SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants
SARS-CoV-2 infection induces beta cell transdifferentiation
QSER1 protects DNA methylation valleys from de novo methylation
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation
Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors
Inducible Pluripotent Stem Cell–Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in <i>RAF1</i> -Associated Noonan Syndrome
Discovery of a drug candidate for GLIS3-associated diabetes
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells
An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery
Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells
Orchestrating liver development