Area of research
Molecular Biology
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, Fungal and yeast genetics research, Polyamine Metabolism and Applications, and Protein Kinase Regulation and GTPase Signaling.
Multi-omics profiling reveals divergent biology and liver microenvironment in HCC of metastatic and de novo origin.
Metabolic reprogramming in hepatocellular carcinoma: mechanisms and therapeutic implications.
Identification of transglutaminase 2 mediated polyaminated proteins in a hepatocellular cancer cell line.
Multi-omics of sorafenib responsiveness in HCC patients
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition.
mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Arginine reprograms metabolism in liver cancer via RBM39
TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes.
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia.
Colitis Is Associated with Loss of the Histidine Phosphatase LHPP and Upregulation of Histidine Phosphorylation in Intestinal Epithelial Cells.
Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice.
mTORC2 regulates auditory hair cell structure and function.
Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis.
ALK signalling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition
mTOR substrate phosphorylation in growth control.
Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages.
Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis.
Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis.
Combining metformin with lactate transport inhibitors as a treatment modality for cancer - recommendation proposal.
Novel roles of mTORC2 in regulation of insulin secretion by actin filament remodeling.
TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes
Elevated arginine levels in liver tumors promote metabolic reprogramming and tumor growth
The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis.
A reference map of sphingolipids in murine tissues
A reference map of sphingolipids in murine tissues.
Regulation of human mTOR complexes by DEPTOR.
mTOR signaling mediates ILC3-driven immunopathology.
Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma.
SusChEM: Theoretical Studies of Inorganic, Organometallic, and Bioinorganic Systems
Theoretical Studies of Inorganic, Organometallic, and Bioinorganic Systems
Theoretical Studies of Inorganic, Organometallic, and Bioinorganic Systems
Theoretical Studies of Inorganic, Organometallic, and Bioinorganic Systems
Support for Argos Data Collection and Location System
Theoretical Studies of Inorganic and Organometallic Systems
Theoretical Studies of Inorganic and Organometallic Systems
Workshop on ENSO and Seasonal to Interannual Climate Variability: Socio-Economic Impacts, Forecasting, and Applications to the Decision-Making Process
Theoretical Studies of Inorganic and Organometallic Systems
Internation TOGA Project Office Periodic Reports
Purchase of a Departmental Computer System
The Purchase of an Electron Paramagnetic Resonance Spectrometer
Acqusitiion of an X-Ray Photoelectron Spectrometer
U.S.A. and WMO Joint Support: International TOGA Project Office
Purchase of a Mass Spectrometer with Accessories
Theoretical Studies of Inorganic and Organometallic Systems
U.S.A. and WMO Joint Support: International TOGA Project Office
Support for the U.S. TOGA (Tropical Ocean Global Atmosphere)Project Office
Theoretical Studies of the Electronic and Molecular Structure of Inorganic and Organometallic Systems (Chemistry)
Theoretical Studies on the Electronic and Molecular Structure of Inorganic and Organometallic Systems
Theoretical Studies on the Electronic and Molecular Structure of Inorganic and Organometallic Systems
Task Order For U.S. Committee For the Global Atmospheric Research Program
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