Area of research
Physiology · Psychiatry and Mental health
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Neuroinflammation and Neurodegeneration Mechanisms, and Neurological Disease Mechanisms and Treatments.
Diagnostic accuracy of plasma p‐tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson’s disease
Exosome-mediated microglia-astrocyte interactions drive neuroinflammation in Parkinson's disease with Peli1 as a potential therapeutic target
LBA69 SKYSCRAPER-03: Phase III, open-label, randomised study of atezolizumab (atezo) + tiragolumab (tira) vs durvalumab (durva) in locally advanced, unresectable, stage III non-small cell lung cancer (NSCLC) after platinum-based concurrent chemoradiation (cCRT)
Atlas of the plasma proteome in health and disease in 53,026 adults
Glymphatic system dysfunction predicts amyloid deposition, neurodegeneration, and clinical progression in Alzheimer's disease
Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside
Plasma metabolic profiles predict future dementia and dementia subtypes: a prospective analysis of 274,160 participants
Whole exome sequencing analyses identified novel genes for Alzheimer's disease and related dementia
Associations of blood cell indices and anemia with risk of incident dementia: A prospective cohort study of 313,448 participants
TMEM106B aggregation in neurodegenerative diseases: linking genetics to function
Circulating polyunsaturated fatty acids, fish oil supplementation, and risk of incident dementia: a prospective cohort study of 440,750 participants
Socioeconomic status, lifestyle and risk of incident dementia: a prospective cohort study of 276730 participants
Associations of liver dysfunction with incident dementia, cognition, and brain structure: A prospective cohort study of 431 699 adults
Trends in the prevalence of cognitive impairment at old age in China, 2002–2018
Additional file 2 of Association between polygenic risk for Alzheimer’s disease and brain structure in children and adults
Tauopathies: new perspectives and challenges
Investigating Casual Associations Among Gut Microbiota, Metabolites, and Neurodegenerative Diseases: A Mendelian Randomization Study
Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology
Evidence-based expert consensus on the management of primary central nervous system lymphoma in China
Tau Toxicity in Neurodegeneration
Association of peripheral immunity with cognition, neuroimaging, and Alzheimer’s pathology
Identifying causal genes for stroke via integrating the proteome and transcriptome from brain and blood
Omics-based biomarkers discovery for Alzheimer's disease
Residential greenness and risk of incident dementia: A prospective study of 375,342 participants
Herpesvirus infections and Alzheimer’s disease: a Mendelian randomization study
Association of Plasma Neurofilament Light With Small Vessel Disease Burden in Nondemented Elderly
Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration
Recommendations for the diagnosis and treatment of paroxysmal kinesigenic dyskinesia: an expert consensus in China
Characterization of Alzheimer’s tau biomarker discordance using plasma, CSF, and PET