Area of research
Physiology · Molecular Biology
Research interest
Research interests include Alzheimer's disease research and treatments, Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, and Dementia and Cognitive Impairment Research.
Low blood levels of selenium, selenoprotein P and GPx3 are associated with accelerated biological aging: results from the Berlin Aging Study II (BASE-II)
DunedinPACE predicts incident metabolic syndrome: cross-sectional and longitudinal data from the Berlin Aging Study II
Cross-sectional and Longitudinal Relationship Between Sex Hormones and 6 Epigenetic Clocks in Older Adults: Results of the Berlin Aging Study II
Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvement
Redefining ALS: Large-scale proteomic profiling reveals a prolonged pre-diagnostic phase with immune, muscular, metabolic, and brain involvement
Blood‐based multivariate methylation risk score for cognitive impairment and dementia
No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer's disease
Change in body weight of older adults before and during the COVID-19 pandemic: longitudinal results from the Berlin Aging Study II
Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer’s disease
DNA methylation age acceleration is associated with risk of diabetes complications
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer’s disease in the EMIF‐AD Multimodal Biomarker Discovery study
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
Relationship Between 5 Epigenetic Clocks, Telomere Length, and Functional Capacity Assessed in Older Adults: Cross-Sectional and Longitudinal Analyses
Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset
Vitamin D supplementation is associated with slower epigenetic aging
Epigenetic aging and perceived psychological stress in old age
Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated in two separate birth cohorts
Seven-CpG DNA Methylation Age Determined by Single Nucleotide Primer Extension and Illumina’s Infinium MethylationEPIC Array Provide Highly Comparable Results
Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans
A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples
Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women
Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach
Cohort profile: follow-up of a Berlin Aging Study II (BASE-II) subsample as part of the GendAge study
BDNF serum concentrations in 2053 participants of the Berlin Aging Study II
A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging
Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults
Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset