Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immunotherapy and Immune Responses, T-cell and B-cell Immunology, Immune Cell Function and Interaction, and Immune Response and Inflammation.
DNA origami vaccines program antigen-focused germinal centers
Cohesin-mediated chromatin organization controls the differentiation and function of dendritic cells
Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance
Ontogeny and Function of Plasmacytoid Dendritic Cells
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses
Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature
Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms
Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells
ETV3 and ETV6 enable monocyte differentiation into dendritic cells by repressing macrophage fate commitment
IL-6 Signaling Attenuates TNF-α Production by Plasmacytoid Dendritic Cells in Rheumatoid Arthritis
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus
Human plasmacytoid dendritic cells mount a distinct antiviral response to virus-infected cells
Adult neural stem cells have latent inflammatory potential that is kept suppressed by <i>Tcf4</i> to facilitate adult neurogenesis
A conserved dendritic-cell regulatory program limits antitumour immunity
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA
Intravital Imaging Reveals Motility of Adult Hematopoietic Stem Cells in the Bone Marrow Niche
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction
The Source and Dynamics of Adult Hematopoiesis: Insights from Lineage Tracing
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells
Nerve associated lung resident interstitial macrophage subset exhibits distinct localization and polarization
Plasmacytoid Dendritic Cells: Development, Regulation, and Function
Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population
Self-DNA at the Epicenter of SLE: Immunogenic Forms, Regulation, and Effects
Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells
<i>Dnase1l3</i>deletion causes aberrations in length and end-motif frequencies in plasma DNA
Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells
Kinetics of adult hematopoietic stem cell differentiation in vivo
Transcription factor Etv6 regulates functional differentiation of cross-presenting classical dendritic cells