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José Baselga

Vall d'Hebron Institute of Oncology ·
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include HER2/EGFR in Cancer Research, PI3K/AKT/mTOR signaling in cancer, Advanced Breast Cancer Therapies, and Cancer Treatment and Pharmacology.
h-index
144
citations
118,476
works
1,385
NIH funding
primary concept
email

Recent publications

Abstract PD3-06: Updated results from DESTINY-breast01, a phase 2 trial of trastuzumab deruxtecan (T-DXd ) in HER2 positive metastatic breast cancer
Cancer Research 2021cited by 62position: middledoi
Updated results from the international phase III ALTTO trial (BIG 2-06/Alliance N063D)
European Journal of Cancer 2021cited by 28position: middledoi
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
Nature Genetics 2020cited by 727position: middledoi
Inhibition of Bruton tyrosine kinase in patients with severe COVID-19.
2020cited by 289position: contributordoi
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer
Nature Genetics 2020cited by 237position: middledoi
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer.
2020cited by 189position: contributordoi
FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer
Cancer Cell 2020cited by 134position: middledoi
Pan-Cancer Efficacy of Vemurafenib in <i>BRAF</i> V600-Mutant Non-Melanoma Cancers
Cancer Discovery 2020cited by 123position: middledoi
Tumor mutational load predicts survival after immunotherapy across multiple cancer types
Nature Genetics 2019cited by 4,333position: middledoi
A view on drug resistance in cancer
Nature 2019cited by 2,678position: middledoi
Tumour lineage shapes BRCA-mediated phenotypes
Nature 2019cited by 405position: middledoi
Double <i>PIK3CA</i> mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
Science 2019cited by 294position: lastdoi
Double <i>PIK3CA</i> mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors
Science 2019cited by 263position: contributordoi
Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
The Lancet Oncology 2019cited by 95position: middledoi
Survival outcomes of the NeoALTTO study (BIG 1–06): updated results of a randomised multicenter phase III neoadjuvant clinical trial in patients with HER2-positive primary breast cancer
European Journal of Cancer 2019cited by 90position: middledoi
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression
Cell Reports 2019cited by 70position: lastdoi
MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer
International Journal of Cancer 2019cited by 31position: middledoi
Genome doubling shapes the evolution and prognosis of advanced cancers
Nature Genetics 2018cited by 678position: middledoi
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer
Journal of Clinical Oncology 2018cited by 621position: middledoi
Ado-Trastuzumab Emtansine for Patients With <i>HER2</i>-Mutant Lung Cancers: Results From a Phase II Basket Trial
Journal of Clinical Oncology 2018cited by 555position: middledoi
Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway
Cancer Cell 2018cited by 519position: middledoi
RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer
Annals of Oncology 2018cited by 420position: middledoi
BRAF Inhibition in <i>BRAF</i> <sup>V600</sup> -Mutant Gliomas: Results From the VE-BASKET Study
Journal of Clinical Oncology 2018cited by 326position: middledoi
Alpelisib Plus Fulvestrant in <i>PIK3CA</i> -Altered and <i>PIK3CA</i> -Wild-Type Estrogen Receptor–Positive Advanced Breast Cancer
JAMA Oncology 2018cited by 260position: middledoi
Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors
JAMA Oncology 2018cited by 214position: middledoi
Phase III study of taselisib (GDC-0032) + fulvestrant (FULV) <i>v</i> FULV in patients (pts) with estrogen receptor (ER)-positive, <i>PIK3CA</i> -mutant (MUT), locally advanced or metastatic breast cancer (MBC): Primary analysis from SANDPIPER.
Journal of Clinical Oncology 2018cited by 140position: firstdoi
Abstract 3596: Biomarkers of response to CDK4/6 inhibitor (CDK4/6i) in hormone receptor (HR) positive and HER2-positive breast cancer (BC) patient-derived xenografts (PDX)
Cancer Research 2018cited by 1position: middledoi
De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017
Annals of Oncology 2017cited by 1,251position: middledoi
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial
The Lancet 2017cited by 1,033position: middledoi
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes
Cell stem cell 2017cited by 840position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Martine Piccart · Tecnológico de Monterrey13 papers (2012–2019)Maurizio Scaltriti · AstraZeneca (Japan)13 papers (2013–2019)David M. Hyman · Mayo Clinic in Florida12 papers (2015–2020)Hope S. Rugo · UCSF Helen Diller Family Comprehensive Cancer Center11 papers (2012–2018)Howard A. Burris · Sarah Cannon9 papers (2012–2018)Gabriel N. Hortobágyi · The University of Texas MD Anderson Cancer Center8 papers (2012–2014)Sarat Chandarlapaty · Organogenesis (United States)8 papers (2013–2018)Kathleen I. Pritchard · Sunnybrook Health Science Centre8 papers (2012–2014)Mario Campone · Centre de Recherche en Cancérologie de Lyon8 papers (2012–2017)Shinzaburo Noguchi · Novartis (Switzerland)8 papers (2012–2014)Michael Gnant · Tolmar (United States)7 papers (2012–2014)Michael F. Berger · Memorial Sloan Kettering Cancer Center6 papers (2013–2018)Javier Cortés · Universidade Nova de Lisboa6 papers (2015–2018)Tarek Sahmoud · Harbin Medical University5 papers (2012–2013)Maria E. Arcila · Molecular Oncology (United States)5 papers (2015–2018)Véronique Dièras · Centre Eugène Marquis5 papers (2012–2018)Neal Rosen · Memorial Sloan Kettering Cancer Center5 papers (2013–2018)David B. Solit · New York Oncology Hematology5 papers (2015–2018)Tetiana Taran · Lublin Oncology Center5 papers (2013–2013)Josep Tabernero · Medical Research Network4 papers (2012–2017)
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