Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Immune cells in cancer, Cancer, Hypoxia, and Metabolism, and Mitochondrial Function and Pathology.
Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding
Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression
Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages
Multi-omics and pharmacological characterization of patient-derived glioma cell lines
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages
Single-cell transcriptomic and spatial analysis reveal the immunosuppressive microenvironment in relapsed/refractory angioimmunoblastic T-cell lymphoma
Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer
Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages
Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages
Circulating tumor DNA integrating tissue clonality detects minimal residual disease in resectable non-small-cell lung cancer
DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas
Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
Systematic analysis of telomere length and somatic alterations in 31 cancer types
EGFR heterogeneity and implications for therapeutic intervention in glioblastoma
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation
TERT Promoter Mutations and Risk of Recurrence in Meningioma
Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
Integration Strategy Is a Key Step in Network-Based Analysis and Dramatically Affects Network Topological Properties and Inferring Outcomes
Inferring Potential microRNA-microRNA Associations Based on Targeting Propensity and Connectivity in the Context of Protein Interaction Network
mirTarPri: Improved Prioritization of MicroRNA Targets through Incorporation of Functional Genomics Data
Community of protein complexes impacts disease association
Systematically characterizing and prioritizing chemosensitivity related gene based on Gene Ontology and protein interaction network
Association study of ACE and eNOS single nucleotide polymorphisms with Henoch-Schönlein purpura nephritis
Prioritizing Cancer Therapeutic Small Molecules by Integrating Multiple OMICS Datasets
Screening for cancer associated MiRNAs through co-gene, co-function and co-pathway analysis