Area of research
Pharmacology · Organic Chemistry
Research interest
Research interests include Janus kinase, Biology, Chemistry, Asthma, KRAS, and MAPK/ERK pathway.
Special Section on Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities–Minireview
Inhaled Janus Kinase (JAK) inhibitors for the treatment of asthma
Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma
A probabilistic method to report predictions from a human liver microsomes stability QSAR model: a practical tool for drug discovery
Retinal Toxicity, in vivo and in vitro, Associated with Inhibition of Nicotinamide Phosphoribosyltransferase
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
Discovery and Optimization of <i>C</i>-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2