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Matthew A. Brown

University of Chicago · US
🔎 Find collaborators in Rheumatology · Immunology →
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Area of research
Rheumatology · Immunology
Research interest
Research interests include Spondyloarthritis Studies and Treatments, Rheumatoid Arthritis Research and Therapies, Psoriasis: Treatment and Pathogenesis, and Systemic Lupus Erythematosus Research.
h-index
128
citations
95,163
works
1,228
NIH funding
primary concept
email

Recent publications

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nature Communications 2025cited by 53position: middledoi
A disease-specific convergence of host and Epstein–Barr virus genetics in multiple sclerosis
Proceedings of the National Academy of Sciences 2025cited by 22position: middledoi
A redefined InDel taxonomy provides insights into mutational signatures
Nature Genetics 2025cited by 11position: middledoi
Medical guidelines for fibrodysplasia ossificans progressiva
JBMR Plus 2025cited by 6position: middledoi
Global epidemiology of spondyloarthritis
Nature Reviews Rheumatology 2025cited by 6position: lastdoi
568: CLINICAL OUTCOMES OF DIFFERENT MICAFUNGIN DOSING STRATEGIES IN OBESE PATIENTS WITH CANDIDEMIA
Critical Care Medicine 2025cited by 1position: middledoi
Multi-omic insights from a multi-ancestry genome-wide meta-analysis of ankylosing spondylitis reveal novel pathways of disease susceptibility
Research Square 2025cited by 1position: firstdoi
Origins and impact of extrachromosomal DNA
Nature 2024cited by 134position: middledoi
A genome-wide association analysis reveals new pathogenic pathways in gout
Nature Genetics 2024cited by 79position: middledoi
Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials
Annals of the Rheumatic Diseases 2024cited by 32position: firstdoi
Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility
Nature Communications 2024cited by 31position: middledoi
Large-Scale Pharmacogenomics Analysis of Patients With Cancer Within the 100,000 Genomes Project Combining Whole-Genome Sequencing and Medical Records to Inform Clinical Practice
Journal of Clinical Oncology 2024cited by 16position: middledoi
Asteroseismology of the Nearby K Dwarf σ Draconis Using the Keck Planet Finder and TESS
The Astrophysical Journal 2024cited by 13position: middledoi
Stretch-activated ion channel TMEM63B associates with developmental and epileptic encephalopathies and progressive neurodegeneration
The American Journal of Human Genetics 2023cited by 40position: middledoi
HLA-B27, axial spondyloarthritis and survival
Annals of the Rheumatic Diseases 2023cited by 28position: lastdoi
Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping
Genome Medicine 2023cited by 27position: middledoi
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders
Nature Communications 2023cited by 21position: middledoi
HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder
The American Journal of Human Genetics 2023cited by 21position: middledoi
Substitution mutational signatures in whole-genome–sequenced cancers in the UK population
Science 2022cited by 280position: middledoi
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab
Nature Communications 2022cited by 81position: middledoi
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features
Nature Genetics 2022cited by 75position: middledoi
Progress in the genetics of uveitis
Genes and Immunity 2022cited by 65position: lastdoi
T cell Repertoire Profiling and the Mechanism by which HLA-B27 Causes Ankylosing Spondylitis
Current Rheumatology Reports 2022cited by 54position: lastdoi
Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling
Arthritis & Rheumatology 2022cited by 47position: middledoi
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements
Nature Communications 2022cited by 45position: middledoi
Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity
Arthritis Research & Therapy 2022cited by 39position: lastdoi
Heterogeneity of axial spondyloarthritis: genetics, sex and structural damage matter
RMD Open 2022cited by 36position: lastdoi
Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients
Children 2022cited by 18position: middledoi
The faecal microbiota is distinct in HLA-B27+ ankylosing spondylitis patients versus HLA-B27+ healthy controls
Clinical and Experimental Rheumatology 2022cited by 14position: middledoi
Ankylosing spondylitis: an autoimmune or autoinflammatory disease?
Nature Reviews Rheumatology 2021cited by 348position: middledoi

Grants

AGS-PRF: A Unified Conceptual Model for the Development of Near-Surface Rotation in Squall Lines
NSF2414969$202,0002024–2026PIRePORTER
Collaborative Research: PurSUiT: Sampling amoeboid protists as a reservoir of unknown/undescribed eukaryotic diversity
NSF2100888$1,131,5172021–2026PIRePORTER
Examining the macroevolutionary trajectories in Amoebozoa, a major lineage of eukaryotes
NSF1456054$832,2592015–2020PIRePORTER
Phylogenetically informed curation of eukaryotic 18S rDNA
NSF1545931$16,6522015–2017PIRePORTER
Engineering Ethics as an Expert Guided and Socially Situated Activity
NSF1338735$299,9692013–2017PIRePORTER

Frequent collaborators

Zhixiu Li · Nanchang University7 papers (2019–2023)Lianne S. Gensler · University of San Francisco6 papers (2014–2024)John D. Reveille · Dartmouth College6 papers (2014–2025) · 4 papers (2019–2022)Tony Kenna · University of Queensland4 papers (2016–2022)Huji Xu · Jiangsu University3 papers (2014–2020) · 3 papers (2021–2022)Anne Barton · University of Manchester3 papers (2015–2021)Michael H. Weisman · Stanford University3 papers (2014–2018)Paul Leo · Queensland University of Technology3 papers (2014–2020)Alex W. Hewitt · Geisinger Health System3 papers (2015–2018)Jamie E. Craig · Johannes Gutenberg University Mainz3 papers (2015–2018) · 3 papers (2021–2022) · 3 papers (2014–2018)Emma L. Duncan · King's College London3 papers (2014–2020)Kathryn P. Burdon · University of Tasmania3 papers (2015–2018)Michael M. Ward · Rush University Medical Center3 papers (2014–2018)Helena Marzo‐Ortega · University of Leeds3 papers (2014–2017)Aideen McInerney‐Leo · University of Queensland3 papers (2014–2020)Ranjeny Thomas · University of Queensland3 papers (2020–2021)
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