Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
German Rheumatism Research Center Berlin and Department of Experimental Rheumatology of the Charité – University School of Medicine Berlin
Selective Depletion of Autoreactive Plasma Cells as a Novel Strategy to Treat Acetylcholine Receptor Antibody-Positive Myasthenia Gravis.
Heterogeneous signaling pathways are critical for the persistence of memory T cells in spleen and bone marrow
Polyfunctional varicella-zoster virus–reactive memory CD4+ T cells reside in human bone marrow
TGFβ links EBV to multisystem inflammatory syndrome in children
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis
TGFβ links EBV to multisystem inflammatory syndrome in children.
Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease
Surface CD69-Negative CD4 and CD8 Bone Marrow-Resident Human Memory T Cells.
Methylomes of human CD4 and CD8 memory T lymphocytes reveal tissue-specific epigenetic signatures for maintenance and recall function
Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease
Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)
EFIS Board 2024–2027: New Leadership for Advancing Immunology in Europe
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow
Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow.
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry
Serum TGF‐β as a predictive biomarker for severe disease and fatality of COVID‐19
Serum TGF-β as a predictive biomarker for severe disease and fatality of COVID-19.
Physiological and Pathophysiological Roles of IgM Fc Receptor (FcµR) Isoforms.
Enhanced Mott cell formation linked with IgM Fc receptor (FcμR) deficiency.
Editorial: Global excellence in cellular immunology: Europe 2021.
In memoriam Av Mitchison (1928–2022)
Recruitment of plasma cells to the bone marrow in primary and secondary immune reactions
B Cell Numbers Predict Humoral and Cellular Response Upon SARS-CoV-2 Vaccination Among Patients Treated With Rituximab.
Resident memory CD4 <sup>+</sup> T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction
Resident memory CD4<sup>+</sup> T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction.
Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells
A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individuals
Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells.
Questioning whether IgM Fc receptor (FcµR) is expressed by innate immune cells.